Circulating betatrophin/ANGPTL8 levels correlate with body fat distribution in individuals with normal glucose tolerance but not those with glucose disorders

Table 2 Correlation analysis of body fat distribution and betatrophin levels in the NGT group

	Betatrophin		Betatrophin (age, sex, and BMI adjusted)		Betatrophin (age, sex, BMI, and TG adjusted)
	r	P value	Partial r	P value	Partial r	P value
WHR	0.319	0.010*	0.175	0.185	0.191	0.151
SAT	− 0.192	0.128	− 0.189	0.151	− 0.199	0.135
VAT	0.364	0.003*	0.239	0.069	0.244	0.064
VAT/SAT	0.425	0.000*	0.339	0.009*	0.355	0.006*
BFR (%)	−0.304	0.015*	−0.275	0.035*	−0.269	0.041*
LUR (%)	−0.236	0.065	0.044	0.740	0.040	0.767
RUR (%)	−0.171	0.184	0.163	0.217	0.156	0.244
LLR (%)	−0.326	0.010*	−0.330	0.011*	−0.324	0.013*
RLR (%)	−0.304	0.016*	−0.288	0.027*	−0.281	0.033*

WHR Waist-to-hip ratio, SAT Subcutaneous adipose tissue, VAT Visceral adipose tissue, VAT/SAT Ratio visceral adipose tissue-to-subcutaneous adipose tissue ratio, BFR Body fat ratio, LUR Left upper limb fat ratio, RUR Right upper limb fat ratio, LLR Left lower limb fat ratio, RLR Right lower limb fat ratio. Statistical significance from Pearson’s (normally distributed data) or Spearman’s (non-normally distributed data) correlation tests. *P values < 0.05 were considered statistically significant

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