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Table 3 Pathological parameters of malign thyroid nodules diagnosed in Bethesda III and IV classes following the resection.

From: Malignancy rates for Bethesda III and IV thyroid nodules: a retrospective study of the correlation between fine-needle aspiration cytology and histopathology

 

AUS/FLUS (N=27)

FN (N=13)

Total (N=40)

P value

Tumor type

 Follicular carcinoma

2 (7.4%)

2 (15.4%)

4 (10%)

0.65a

 Papillary thyroid carcinoma

22 (81.5%)

9 (69.2%)

31 (77.5%)

 Others

3 (11.1%)

2 (15.4%)

5 (12.5%)

Tumor size (cm of the largest nodule)

1.97 ± 0.19

1.77 ± 0.20

1.91 ± 0.15

0.78b

Encapsulation

3 (11.1%)

0

3 (75%)

0.54c

Tumor invasion into thyroid capsule

6 (22.2%)

6 (46.2%)

12 (30%)

0.24c

Extrathyroidal extension

2 (7.4%)

1 (7.7%)

3 (75%)

0.97c

Lymphovascular invasion

2 (7.4%)

1 (7.7%)

3 (75%)

0.97c

  1. AUS Atypia of undetermined significance
  2. FLUS Follicular lesion of undetermined significance
  3. FN Follicular neoplasia
  4. aChi-squared Test for Independence
  5. bNonparametric Mann-Whitney Test
  6. cChi-square Test