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Table 2 Baseline and changes in clinical and laboratory parameters at 3 and 6 months after bariatric surgery

From: Changes in plasma aldosterone level after weight loss by bariatric surgery in morbidly obese patients

 

Baseline [n = 14]

Month 3 [n = 14]

Month 6 [n = 13]

BW [kg]

161.6 + 39.4

134.6 + 32.7***

118.6 + 33.4***

BMI [kg/m2]

56.7 + 13.5

47.1 + 11.1***

40.6 + 9.9***

Waist [cm]

153.6 + 32.2

131.5 + 25.0***

118.6 + 33.4***

Percent of fat

55.46 + 6.23

49.81 + 5.64***

–

SBP [mmHg]

126.6 + 19.0

109.1 + 10.5**

104.5 + 9.0**

DBP [mmHg]

75.7 + 11.0

67.4 + 9.6

63.7 + 7.9*

FPG [mg/dl]

97.6 + 12.6

93.3 + 23.0

83.3 + 5.9*

HbA1c [%]

5.8 + 0.6

5.5 + 0.4

5.5 + 0.4

HbA1c [mmol/mol]

40 + 1.8

37 + 1.2

37 + 1.2

Total cholesterol [mg/dl]

206.1 + 46.9

179.4 + 33.3

187.6 + 25.9

HDL-C [mg/dl]

38.9 + 12.7

32.0 + 6.0*

34.7 + 7.3

Triglyceride [mg/dl]

159.1 + 61.8

114.6 + 35.6**

102.9 + 38.5**

LDL-C [mg/dl]

133.9 + 43.4

127.6 + 28.8

135.7 + 23.1

PAC [ng/dl]

14.3 + 8.0

7.5 + 5.5**

8.0 + 6.6*

DRC [ng/L]

11.4 + 8.3

7.4 + 2.5

9.1 + 7.7

Potassium [mEq/l]

4.5 + 0.26

3.7 + 0.26

3.6 + 0.26

Creatinine [mg/dl]

0.76 + 0.16

0.70 + 0.17

0.69 + 0.15*

eGFR [ml/min/1.73m2]

119.4 + 16.0

126.2 + 16.3

126.9 + 15.8*

  1. Abbreviations: BW body weight, PAC plasma aldosterone concentration, DRC direct renin concentration, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, HDL- C high – density lipoprotein cholesterol, LDL-C low – density lipoprotein cholesterol, eGFR estimated glomerular filtration rate
  2. * P-value < 0.025 compared with baseline
  3. ** P-value < 0.005 compared with baseline
  4. *** P-value < 0.0005 compared with baseline
  5. P-value adjusted by Bonferroni correction
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BMC Endocrine Disorders

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