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Table 3 Multivariate analysis for Overall Survival (OS) and prognostic score

From: Effect of metastatic site on survival in patients with neuroendocrine neoplasms (NENs). An analysis of SEER data from 2010 to 2014

Parameter

P value

Hazard Ratio

95% CI

Score

Original Site

Lung

<.0001

2.901

2.027

4.15

2.9

Other

2.541

1.836

3.516

2.5

Pancreas

1.502

1.091

2.069

1.5

Bowel

1

  

1

Metastasis location

Bone

0.0066

1.412

0.965

2.065

1.4

Brain

1.666

1.177

2.357

1.7

Liver

1.677

1.226

2.294

1.7

Lung

1

  

1

Grade

1

<.0001

1

  

1

2

1.348

1.011

1.797

1.3

3&4

4.534

3.545

5.799

4.5

Age

  < 60

<.0001

1

  

1

60–70

1.257

1.028

1.537

1.3

  > 70

2.062

1.687

2.519

2.1

Gender

Male

0.0007

1.328

1.127

1.565

1.3

Female

1

  

1

Histology

High grade /atypical

<.0001

2.062

1.525

2.787

2.1

Pancreatic

1.894

0.881

4.071

1.9

Typical

1

  

1

Tumor size

  > 35

0.0082

1.274

1.065

1.525

1.3

  < =35

1

  

1

Score group

Frequency

Percent

Cumulative

frequency

Cumulative

percent

Low: < 9.5

516

32.8

516

32.8

Medium: 9.5 -

13

537

34.14

1053

64.94

High: >13

520

33.06

1573

100

Frequency Missing = 432

  1. Total score is the scores sum of non-missing variables. Its minimum and maximum are 7 and 15.9, respectively