Table 1 Diagnostic value of US and USE for the diagnostic of malignant thyroid nodules
Criteria | Benign | Malignant | Sensitivity (%) | Specificity (%) | Accuracy (%) | PPV (%) | NPV (%) | P |
|---|---|---|---|---|---|---|---|---|
Microcalcification | ||||||||
 Yes | 211 | 416 | 49.9 | 65.6 | 56.4 | 66.3 | 48.9 | <0.01 |
 no | 400 | 318 |  |  |  |  |  |  |
Taller than wide | ||||||||
 yes | 55 | 309 | 37.1 | 91.0 | 59.8 | 84.9 | 51.4 | <0.01 |
 no | 556 | 525 |  |  |  |  |  |  |
Irregular margins | ||||||||
 Yes | 525 | 83 | 93.9 | 14.1 | 60.1 | 59.9 | 62.8 | <0.01 |
 no | 86 | 51 |  |  |  |  |  |  |
ETE | ||||||||
 Yes | 469 | 693 | 83.0 | 23.2 | 57.7 | 59.6 | 50.0 | <0.01 |
 No | 142 | 141 |  |  |  |  |  |  |
Disrupted rim calcification | ||||||||
 Yes | 7 | 39 | 4.7 | 98.9 | 44.4 | 84.8 | 43.2 | <0.01 |
 No | 604 | 795 |  |  |  |  |  |  |
Kwak’s TI-RADS | ||||||||
 4a | 5 | 2 | 62.2 | 70.2 | 65.6 | 74.0 | 57.7 | <0.01 |
 4b | 424 | 313 |  |  |  |  |  |  |
 4c | 182 | 367 |  |  |  |  |  |  |
 5 | 0 | 152 |  |  |  |  |  |  |
Elasticity score | ||||||||
  > 3 | 240 | 771 | 92.4 | 60.7 | 79.0 | 76.3 | 85.5 | <0.01 |
  ≤ 3 | 371 | 63 |  |  |  |  |  |  |
SR value | ||||||||
  > 2.99 | 305 | 676 | 81.1 | 50.1 | 68.9 | 65.9 | 67.9 | <0.01 |
  ≤ 2.99 | 306 | 158 |  |  |  |  |  |  |