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Table 2 Prospective associations (hazard ratios) between leptin and adiponectin with incident type 2 diabetes in the total sample population and by sex

From: Associations of leptin and adiponectin with incident type 2 diabetes and interactions among African Americans: the Jackson heart study

 TotalSex
 Sample Population (n = 2656)
Type 2 diabetes cases (n = 455)
Male (n = 948)
Type 2 diabetes cases (n = 169)
Female (n = 1708)
Type 2 diabetes cases (n = 286)
Continuous AdipokinesModel 1*Model 2Model 1*Model 2Model 1*Model 2
HR95% CIHR95% CIHR95% CIHR95% CIHR95% CIHR95% CI
Log Leptin (ng/mL)1.29(1.05, 1.58)0.99(0.80, 1.22)1.33(1.05, 1.69)1.00(0.78, 1.28)1.24(0.94, 1.64)0.99(0.74, 1.31)
Log Adiponectin (ng/mL)0.57(0.49, 0.67)0.73(0.61, 0.86)0.68(0.52, 0.88)0.80(0.62, 1.04)0.52(0.42, 0.63)0.68(0.55, 0.84)
  1. *Model 1: Adjusted for sex, age, BMI, waist circumference, systolic blood pressure, anti-hypertensive medication, triglycerides, HDL-cholesterol, antihyperlipidemic medication, smoking, alcohol consumption, physical activity, and education level
  2. †Model 2: Adjusted for model 1 variables and HOMA-IR