Associations of leptin and adiponectin with incident type 2 diabetes and interactions among African Americans: the Jackson heart study

Table 2 Prospective associations (hazard ratios) between leptin and adiponectin with incident type 2 diabetes in the total sample population and by sex

	Total				Sex
	Sample Population (n = 2656) Type 2 diabetes cases (n = 455)				Male (n = 948) Type 2 diabetes cases (n = 169)				Female (n = 1708) Type 2 diabetes cases (n = 286)
*Continuous Adipokines*	Model 1*		*Model 2*†		Model 1*		*Model 2*†		Model 1*		*Model 2*†
*Continuous Adipokines*	HR	95% CI	HR	95% CI	HR	95% CI	HR	95% CI	HR	95% CI	HR	95% CI
Log Leptin (ng/mL)	1.29	(1.05, 1.58)	0.99	(0.80, 1.22)	1.33	(1.05, 1.69)	1.00	(0.78, 1.28)	1.24	(0.94, 1.64)	0.99	(0.74, 1.31)
Log Adiponectin (ng/mL)	0.57	(0.49, 0.67)	0.73	(0.61, 0.86)	0.68	(0.52, 0.88)	0.80	(0.62, 1.04)	0.52	(0.42, 0.63)	0.68	(0.55, 0.84)

*Model 1: Adjusted for sex, age, BMI, waist circumference, systolic blood pressure, anti-hypertensive medication, triglycerides, HDL-cholesterol, antihyperlipidemic medication, smoking, alcohol consumption, physical activity, and education level
†Model 2: Adjusted for model 1 variables and HOMA-IR

ISSN: 1472-6823