Fig. 2From: A putative role for the aryl hydrocarbon receptor (AHR) gene in a patient with cyclical Cushing’s diseaseAHR and AIP tumour immunohistochemistry (100x magnification). a. Only cytoplasmic AHR staining was observed in the patient’s corticotrophinoma. b, c. Both cytoplasmic and nuclear AHR staining was observed in control corticotrophinoma specimens from two men with non-cyclical Cushing’s disease and no AHR variants. d-f. Cytoplasmic and membranous staining for the AHR chaperone, AIP, was found in the corticotrophinomas from the patient (d) and the two controls (e, f)Back to article page