Table 3 Blood steroid profiles of patients with PA or PASCS
From: Clinical characterization of patients with primary aldosteronism plus subclinical Cushing’s syndrome
PA (n = 45) | PASCS (n = 14) | PA vs. PASCS | |
|---|---|---|---|
Mean ± SD Median [IQR] | Mean ± SD Median [IQR] | P value | |
PAC, pg/mL | 208.0 [273.0–159.8] | 255.0 [713.3–153.5] | < 0.005 |
PRA, ng/mL/h | 0.2 [0.3–0.1] | 0.15 [0.3–0.1] | NS |
PAC/PRA ratio | 1258.3 [1956.3–643.1] | 1450.0 [5010.0–529.4] | < 0.005 |
PRA in the furosemide upright posture challenge test, ng/mL/h | 0.4 [0.7–0.2] | 0.2 [0.8–0.15] | NS |
PAC in the saline infusion test, pg/mL | 160.0 ± 166.5 | 313.5 ± 364.8 | NS |
PAC/PRA ratio in the captopril challenge test | 730.7 ± 745.7 | 3028.5 ± 3648.9 | < 0.001 |
PAC in the captopril challenge test, pg/mL | 149.0 ± 94.2 | 348.6 ± 340.1 | < 0.005 |
Cortisol, μg/dL | 12.4 ± 4.3 | 16.4 ± 6.6 | < 0.05 |
ACTH, pg/mL | 23.1 ± 13.6 | 18.2 ± 18.8 | NS |
DHEAS, μg/dL | 111.5 ± 75.1 | 78.5 ± 129.8 | NS |
ACTH in the CRH challenge test, pg/mL | 57.1 ± 10.8 | 18.9 ± 8.9 | < 0.005 |