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Table 1 Clinical and biochemical characteristics of participants

From: Angiopoietin-like 2 is a potential biomarker for diabetic foot patients

Variables

Diabetic control (n = 40)

DFU (n = 28)

P value

Age (year)

63.55 ± 2.22

65.32 ± 2.65

0.6101

Sex (Female,%)

16 (40.0%)

13 (46.4%)

0.5981

Drinking(n,%)

6 (15.0%)

4 (14.3%)

0.0008*

Diabetes duration (year)

11.99 ± 1.47

14.43 ± 1.79

0.2957

SBP (mmHg)

126.4 ± 3.53

134.46 ± 4.22

0.1483

DBP (mmHg)

75.20 ± 1.86

75.57 ± 2.22

0.8985

FBG (mmol/L)

9.69 ± 0.65

8.59 ± 0.78

0.6259

HbA1c(%)

9.86 ± 0.39

9.13 ± 0.45

0.2236

TC (mmol/L)

3.98 ± 0.20

4.02 ± 0.24

0.8846

TG (mmol/L)

1.72 ± 0.16

1.45 ± 0.20

0.2913

HDL-c (mmol/L)

0.97 ± 0.04

0.90 ± 0.04

0.2208

LDL-c (mmol/L)

2.46 ± 0.15

2.59 ± 0.18

0.5831

ALT(U/L)

20.23 ± 3.75

23.60 ± 4.43

0.5625

AST(U/L)

16.38 ± 3.17

24.11 ± 3.73

0.1197

γ-GT(U/L)

25.13 ± 6.54

38.48 ± 7.86

0.1965

WBC(109/L)

7.67 ± 0.68

10.15 ± 0.81

0.0220*

Neutrophil(%)

65.10 ± 2.12

70.92 ± 2.53

0.0828

Monocytes(%)

9.38 ± 1.75

14.27 ± 2.09

0.7780

Lymphocyte(%)

22.01 ± 1.46

12.57 ± 1.74

0.0001*

CRP (ng/mL)

13.95 ± 9.56

56.12 ± 10.93

0.0052*

ESR (mm/h)

15.56 ± 4.81

71.78 ± 5.56

< 0.0001*

Hypertension(n,%)

28 (70.0%)

17 (60.7%)

0.4270

Coronary heart disease(n,%)

10 (25.0%)

8 (28.6%)

0.7431

Cerebral vascular disease(n,%)

13 (32.5%)

8 (28.6%)

0.7294

Diabetic retinopathy(n,%)

20 (50.0%)

10 (35.7%)

0.2429

Diabetic nephropathy(n,%)

15 (37.5%)

7 (25.0%)

0.2782

Amputation(n,%)

0 (0.0%)

10 (35.7%)

–

  1. SBP Systolic blood pressure, DBP Diastolic blood pressure, FBG Fasting plasma glucose, HbA1c Glycated hemoglobin A1c, TC Total cholesterol, TG Triglyceride, HDL-c HDL cholesterol, LDL-c LDL cholesterol, ALT Alanine aminotransferase, AST Aspartate aminotransferase, γ-GT γ-glutamyl transpeptidase, WBC White blood cell, CRP C-reactive protein, ESR Erythrocyte sedimentation rate. * indicates the difference between groups reaching significance