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Table 3 Associations of GDM, serum FT4 levels, and interaction between GDM and serum FT4 on the development of T2DM using pooled logistic regression analyses

From: Assessment of the simultaneous effect of hypothyroidism and thyroid autoimmunity with gestational diabetes on the incidence of type 2 diabetes

Variables

Unadjusted model

Model 1

Model 2

Model 3

OR (95% CI)

P-value

OR (95% CI)

P-value

OR (95% CI)

P-value

OR (95% CI)

P-value

FT4(ng/dL)

1.02 (0.94, 1.10)

0.70

1.02 (0.94, 1.11)

0.63

1.01 (0.93, 1.10)

0.76

1.0.6 (0.97, 1.15)

0.23

GDM

1.05 (0.15, 7.10)

0.96

0.95 (0.13, 6.67)

0.96

0.42 (0.06, 3.07)

0.39

0.58 (0.08, 4.35)

0.60

GDM × FT4

0.95 (0.81, 1.13)

0.60

0.94 (0.79, 1.11)

0.48

0.89 (0.75, 1.06)

0.19

0.91 (0.77, 1.09)

0.31

  1. Model 1: adjusted for age
  2. Model 2: adjusted for age, BMI, educational status, smoking and family history of DM
  3. Model 3: adjusted for serum triglycerides, total and HDL-cholesterol levels, systolic blood pressure, diastolic blood pressure, and FBS
  4. GDM gestational diabetes, T2DM type 2 diabetes mellitus, FT4 free thyroxin