Relationship between hemoglobin and insulin-like growth factor-1 in children and adolescents with idiopathic short stature

Table 3 Threshold effect analysis for the relationship between Hb and IGF-1 SDS

Models	IGF-1 SDS
Models	Adjusted B (95%CI)	P value
Model I
One line slope (n = 178)	0.03 (0.01, 0.05)	0.001
Model II
Hemoglobin’s inflection point	145
< 145 (n = 162)	0.05 (0.02, 0.07)	< 0.001
> 145 (n = 16)	−0.15 (− 0.23, − 0.06)	0.001
LRT test	0.044

Model I, linear analysis; Model II, nonlinear analysis. LRT test, logarithmic likelihood ratio test (p-value< 0.05 indicates that Model II is significantly different from Model I, which indicates a nonlinear relationship); adjustment variables: age, sex, BMI, TC, pubertal stage
BMI body mass index, TC total cholesterol
B unstandardized regression coefficient; P < 0.05 was considered to be statistically significant

ISSN: 1472-6823