Skip to main content

Table 3 Stratification of hormonal, antropometric, clinical, radiologic, biochemical and metabolic parameters in ACS patients by age

From: The prevalence and characteristics of non-functioning and autonomous cortisol secreting adrenal incidentaloma after patients’ stratification by body mass index and age

Variable

Age (years)

P value

< 40

N = 3

40–49

N = 11

50–59

N = 40

60–69

N = 37

70–79

N = 36

> 79

N = 15

Basal serum cortisol (nmol/l)

b

339 (239-)

372 (320.5–565.5)

444 (362.5–510.5)

478.5 (372–606.5)

475 (451–604)

0.123

Serum cortisol after ODST (nmol/l)a

56 (54.1-)

62.3 (52–92.7)

70.25 (57.45–93.18)

67.9 (54.95–94.35)

62.95 (56.8–84.28)

67 (52.4–76.4)

0.774

Basal DHEAS (μmol/L)

b

1.85 (0.5–3)

0.9 (0.43–1.8)

0.9 (0.5–1)

0.44 (0.38–1.03)

0.9 (0.4–1.68)

0.445

DHEAS after ODST (μmol/L)

b

0.8 (0.2–1.2)

0.5 (0.3–1.1)

0.5 (0.3–0.85)

0.5 (0.2–0.7)

1 (0.25–1.8)

0.716

Aldosteron (nmol/l)

b

0.31 (0.13–0.62)

0.2 (0.11–0.28)

0.21 (0.14–0.42)

0.21 (0.07–0.35)

0.23 (0.14–0.27)

0.870

Plasma Renin Activity – PRA (μg/l/h)

b

0.21 (0.06–2.69)

0.49 (0.15–1.06)

0.68 (0.34–2.98)

0.94 (0.34–2.32)

0.61 (0.18–1.97)

0.719

TSH (mE/l)

4.51 (2.4-)

0.39 (0.34–1.31)

1.37 (0.71–2.36)

6.15 (5.73–7.48)

0.8 (0.48–5.85)

1.26 (0.51–3.15)

0.001

Pairwise comparisons

40–49 vs. 60–69 P = 0.002

50–59 vs. 60–69 P = 0.021

60–69 vs. 70–79 P = 0.025

Body mass (kg)

75 (74.6-)

67.3 (62.3–75)

83.1 (67.5–92.2)

73 (62.3–89.3)

76 (67.7–80.8)

70.15 (64.48–82.85)

0.061

BMI (kg/m2)

27.76 (25.81-)

25.27 (22.58–26.91)

28.91 (25.61–31.9)

29.34 (22.98–32.12)

27.59 (26.13–33.46)

28.55 (25.61–30.92)

0.227

Systolic blood pressure (mm Hg)

122 (119–122)

120 (115–140)

140.5 (125.75–150.75)

145 (112–150)

146.5 (131.25–164.5)

150 (135–160)

0.038

Diastolic blood pressure (mm Hg)

82 (76–82)

75 (75–90)

80 (75–90)

73 (68–85)

75 (70–80)

74 (65–82)

0.037

Heart rate

91 (51–91)

80.5 (70.25–94.5)

78 (65–84.75)

77 (67–84)

70 (66.25–84.5)

82 (71.75–90.5)

0.637

Fasting glucose (mmol/liter)

4.7 (4.6-)

4.6 (4.28–5.1)

5.15 (4.93–5.98)

5.5 (5.1–6.38)

5.4 (5–5.98)

6.15 (5.33–6.55)

0.003

Pairwise comparisons

40–49 vs. 60–69 P = 0.021

40–49 vs. > 79 P = 0.006

Total cholesterol (mmol/liter)

5.4 (5.3-)

5.05 (5-)

5.7 (4.7–6.5)

5 (4.1–5.9)

4.6 (4–5.2)

5 (3.6–5.3)

0.019

Pairwise comparisons

50–59 vs. 70–79 P = 0.014

HDL (mmol/liter)

1.3 (1-)

1.45 (1.3-)

1.2 (1–1.6)

1.3 (1.1–1.9)

1.2 (1.1–1.5)

1.05 (0.75–1.1)

0.125

LDL (mmol/liter)

3.6 (3.2-)

2.85 (2.7-)

3.6 (2.9–4.4)

3 (2.5–3.5)

2.7 (2.1–3)

2.7 (1.4–3.7)

0.021

Pairwise comparisons

50–59 vs. 70–79 P = 0.010

Triglycerides (mmol/liter)

2.7 (1.2-)

1.55 (1.1-)

1.6 (1–2)

1.6 (1.2–2)

1.7 (1.2–2.1)

1.9 (1.15–2.85)

0.660

Creatinine (mmol/liter)

69 (64-)

69 (59–74)

67.5 (60.5–74.75)

80 (71–90)

74 (67–92)

79.5 (68.5–96)

0.006

Pairwise comparisons

50–59 vs. 60–69 P = 0.023

Sodium (mmol/liter)

141 (137-)

141 (139–143)

142 (140–144)

142 (141–143)

142 (141–144)

141.5 (139.75–144)

0.630

  1. afor 70 patients, data were provided as below 27.6, for 20 below 28 and for 1 below 31.3
  2. bdata available for only 1 patient or no patients
  3. Data are given as Median (25–75%)