Skip to main content

Table 1 The characteristics of diabetic patients

From: Neutrophil count as a reliable marker for diabetic kidney disease in autoimmune diabetes

Ā 

T1D

P

LADA

P

Normoalbuminuria

Microalbuminuria

Macroalbuminuria

Normoalbuminuria

Microalbuminuria

Macroalbuminuria

Number

204

10

12

Ā 

61

10

8

Ā 

Age (yr)

21.67Ā±14.92

28.50Ā±28.66

33.50Ā±17.06*

0.017

52.46Ā±10.48

58.90Ā±14.14

57.00Ā±9.26

0.156

Gender (male/female)

100/104

3/7

5/7

0.456

35/26

7/3

4/4

0.667

Duration of diabetes (yr)

5.13Ā±5.05

7.27Ā±7.59

11.03Ā±5.12*

<0.001

5.42Ā±5.45

10.40Ā±5.99*

12.56Ā±6.54*

0.001

BMI (kg/mĀ²)

18.95Ā±3.20

19.00Ā±2.73

21.01Ā±2.31*

0.110

21.59Ā±2.79

22.86Ā±3.62

21.96Ā±2.42

0.429

Smoker (%)

35.3

40.0

41.7

0.870

24.6

50.0

37.5

0.231

WHR

0.84Ā±0.07

0.83Ā±0.08

0.87Ā±0.07

0.296

0.89Ā±0.06

0.91Ā±0.05

0.88Ā±0.06

0.530

SBP (mmHg)

112.94Ā±15.53

114.20Ā±20.91

139.42Ā±34.21*āˆ†

<0.001

122.72Ā±17.23

133.90Ā±22.83

137.75Ā±24.26*

0.039

DBP (mmHg)

70.56Ā±12.69

75.00Ā±16.21

81.67Ā±16.46*

0.012

77.00Ā±9.82

79.90Ā±15.50

85.13Ā±10.74

0.121

HbA1c (%)

8.37Ā±2.19

7.63Ā±1.85

7.48Ā±1.40

0.228

9.45Ā±2.35

9.69Ā±2.53

9.89Ā±2.17

0.864

FBG (mmol/l)

9.17Ā±4.56

7.60Ā±3.08

10.63Ā±4.78

0.315

8.31Ā±4.31

8.07Ā±3.55

6.56Ā±3.73

0.579

PBG (mmol/l)

16.01Ā±7.17

14.88Ā±6.84

13.27Ā±6.56

0.409

13.50Ā±6.18

12.66Ā±4.92

11.81Ā±5.81

0.746

FCP (pmol/l)a

25.05 (5.50, 89.58)

10.05 (5.50,44.18)

5.50 (5.50,157.50)

0.405

90.00 (30.85,163.75)

136.75 (37.53,224.88)

70.55 (9.48, 188.48)

0.771

PCP (pmol/l) a

41.00 (5.70,215.08)

30.60 (5.85,86.50)

17.1 (5.50,126.30)

0.512

179.90 (56.50,312.78)

251.65 (76.80,593.80)

202.30 (13.80,255.23)

0.778

TG (mmol/l) a

0.74 (0.58,1.11)

0.86 (0.49,1.23)

0.84 (0.65,1.25)

0.422

0.93 (0.68, 1.17)

1.31 (0.86, 1.70)

1.30 (0.91, 1.54)

0.068

TC (mmol/l)

4.28Ā±0.91

4.15Ā±0.83

4.63Ā±1.26

0.416

4.19Ā±0.72

4.07Ā±0.82

3.94Ā±0.98

0.680

LDL-c (mmol/l)

2.42Ā±0.78

2.24Ā±0.83

2.72Ā±1.04

0.354

2.43Ā±0.64

2.38Ā±0.78

2.37Ā±0.94

0.965

HDL-c (mmol/l) a

1.45 (1.20,1.67)

1.55 (1.35,1.75)

1.48 (1.30,1.64)

0.574

1.29 (1.13, 1.59)

1.34 (0.91, 1.42)

1.18 (0.94, 1.45)

0.241

Albumin (g/l))

42.37Ā±4.08

41.72Ā±3.65

36.02Ā±7.87*āˆ†

<0.001

37.44Ā±2.96

36.38Ā±2.91

33.21Ā±3.92*āˆ†

0.003

TBIL (umol/l)

12.26Ā±5.35

11.68Ā±3.62

9.46Ā±4.00

0.194

12.14Ā±4.40

10.78Ā±5.84

7.92Ā±2.74

0.081

DBIL (umol/l)

3.92Ā±1.94

3.87Ā±1.08

3.13Ā±1.66

0.382

3.88Ā±1.44

3.28Ā±1.65

2.64Ā±1.18

0.073

UA (umol/l)

255.92Ā±69.79

289.92Ā±78.39

312.02Ā±95.63*

0.018

230.89Ā±53.26

303.57Ā±63.54*

351.35Ā±92.66*

<0.001

EGFR (ml/(min*1.73mĀ²))a

139.15 (111.45-168.47)

110.36 (72.18-135.87)*

57.24 (50.42-116.46)*

0.001

102.23 (80.56-124.21)

72.70 (47.20-144.44)

59.29 (42.45-96.85)*

0.022

No medication

0

0

0

Ā 

0

0

0

Ā 

Oral hypoglycemic agent

0

0

0

Ā 

4

1

0

Ā 

Insulin

204

10

12

Ā 

29

4

4

Ā 

Oral hypoglycemic agent + insulin

0

0

0

Ā 

28

5

4

Ā 
  1. Data are expressed as mean Ā± SD or median (interquartile range) as appropriate. Compared with the normalalbuminuria group: *p < 0.05; Compared with the microalbuminuria group: āˆ† p < 0.05; aNon-parametric kruskal-wallis method was used to test the differences among the three groups.
  2. Abbreviations: T1D type 1 diabetes, LADA latent autoimmune diabetes in adults, BMI body mass index, WHR waist to hip ratio, TG triglycerides, TC total cholesterol, HDL-c high density lipoprotein cholesterol, LDL-c low density lipoprotein cholesterol, TBIL total bilirubin, DBIL direct bilirubin, EGFR estimated glomerular filtration rate, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, PBG 2h postprandial blood glucose, FCP fasting C-peptide, PCP 2h postprandial C-peptide, UA uric acid