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Table 2 Genotypic and allelic distribution in T2D and CS

From: Leu72Met polymorphism of GHRL gene decreases susceptibility to type 2 diabetes mellitus in a Mexican population

  Frequency n (%)     
Genotype CS T2D p OR IC95% pb
Leu72Leua 79 (63.2) 127 (79.9)   – – –
Leu72Met 43 (34.4) 28 (17.6) < 0.050 0.41 0.23–0.70 NS
Met72Met 3 (2.4) 4 (2.5)   0.83 0.18–3.81 NS
Allele
 Leua 201 (80.4) 282 (88.7)   – – –
 Met 49 (19.6) 36 (11.3) < 0.050 0.40 0.23–0.70 ≤0.001
  1. NS non-significant. Genotypes are in Hardy-Weinberg equilibrium; Data was analyzed by Chi squared test. aGenotype and allele of reference. bAdjusted by age, body weight and BMI using multivariate logistic regression analysis
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BMC Endocrine Disorders

ISSN: 1472-6823

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