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Table 2 Genotypic and allelic distribution in T2D and CS

From: Leu72Met polymorphism of GHRL gene decreases susceptibility to type 2 diabetes mellitus in a Mexican population

 

Frequency n (%)

    

Genotype

CS

T2D

p

OR

IC95%

pb

Leu72Leua

79 (63.2)

127 (79.9)

 

–

–

–

Leu72Met

43 (34.4)

28 (17.6)

< 0.050

0.41

0.23–0.70

NS

Met72Met

3 (2.4)

4 (2.5)

 

0.83

0.18–3.81

NS

Allele

 Leua

201 (80.4)

282 (88.7)

 

–

–

–

 Met

49 (19.6)

36 (11.3)

< 0.050

0.40

0.23–0.70

≤0.001

  1. NS non-significant. Genotypes are in Hardy-Weinberg equilibrium; Data was analyzed by Chi squared test. aGenotype and allele of reference. bAdjusted by age, body weight and BMI using multivariate logistic regression analysis
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BMC Endocrine Disorders

ISSN: 1472-6823

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