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Table 3 Frequency and Severity of Injection Site Reactions, All Patients

From: Patient reported outcome data from acromegaly patients treated with injectable somatostatin receptor ligands (SRLs) in routine clinical practice

Injection Site Reaction

Experienced % Yes (Na)

Mild % (nb)

Moderate % (nb)

Severe % (nb)

Pain at injection site during injection

83% (87)

56% (49)

31% (27)

13% (11)

Pain at injection site several hours after injection

68% (71)

60% (43)

32% (23)

7% (5)

Pain at injection site several days after injection

49% (51)

65% (33)

28% (14)

8% (4)

Bruising at the injection site(s)

45% (47)

70% (33)

30% (14)

0% (0)

Swelling at the injection site(s)

47% (49)

65% (32)

33% (16)

2% (1)

Nodules (knots and bumps under the skin) at the injection site(s)

63% (66)

47% (31)

42% (28)

11% (7)

Scar tissue/hardness of the skin at the injection site(s)

42% (44)

41% (18)

46% (20)

14% (6)

  1. aOf total sample
  2. bOf those who reported experiencing the injection site reaction