Table 2 Frequency, Severity, and Pattern of Symptoms for Patients Whose IGF-1 < = 1 ULN; N = 37
Symptom | Experienced Symptom Yes % (N) | Reported Severity | Pattern of Symptom Occurrence | ||||||
|---|---|---|---|---|---|---|---|---|---|
Mild %a(n) | Moderate %a(n) | Severe %a(n) | Constant %a(n) | Right After Injection %a(n) | Middle of Cycle %a(n) | End of Cycle %a(n) | Not sure %a(n) | ||
Headache | 70% (26) | 42% (11) | 27% (7) | 31% (8) | 46% (12) | 8% (2) | 0% (0) | 35% (9) | 12% (3) |
Fatigue/ weakness/ feeling tired | 73% (27) | 22% (6) | 48% (13) | 30% (8) | 82% (22) | 0% (0) | 4% (1) | 7% (2) | 7% (2) |
Excess sweating | 57% (21) | 52% (11) | 33% (7) | 14% (3) | 43% (9) | 10% (2) | 5% (1) | 19% (4) | 24% (5) |
Joint pain | 76% (28) | 25% (7) | 43% (12) | 32% (9) | 64% (18) | 0% (0) | 0% (0) | 29% (8) | 7% (2) |
Swelling of soft tissue | 76% (28) | 36% (10) | 36% (10) | 29% (8) | 43% (12) | 7% (2) | 4% (1) | 36% (10) | 11% (3) |
Carpal tunnel syndrome | 57% (21) | 71% (15) | 19% (4) | 10% (2) | 67% (14) | 0% (0) | 0% (0) | 24% (5) | 10% (2) |
Vision problem | 49% (18) | 61% (11) | 22% (4) | 17% (3) | 61% (11) | 0% (0) | 6% (1) | 6% (1) | 28% (5) |
Snore | 51% (19) | 53% (10) | 32% (6) | 16% (3) | 68% (13) | 5% (1) | 0% (0) | 11% (2) | 16% (3) |
Acro-fog | 76% (28) | 18% (5) | 50% (14) | 32% (9) | 89% (25) | 0% (0) | 0% (0) | 7% (2) | 4% (1) |