Table 4 Associations between the changes in s-zonulin and the changes in the factors of interest after the two weight-loss interventions
Change in covariate | Overall change | Change after conservative weight loss intervention | Change after bariatric surgery | Interaction | ||||
|---|---|---|---|---|---|---|---|---|
B (95% CI) | p-values | B (95% CI) | p-values | B (95% CI) | p-values | B (95% CI) | p-values | |
Body mass index (kg/m2) | 0.9 (− 1.5 to 3.3) | 0.46 | 3.2 (−0.9 to 7.2) | 0.27 | −0.4 (− 3.4 to 2.6) | 0.80 | 3.5 (− 1.5 to 8.6) | 0.17 |
Weight (kg) | −0.7 (− 3.9 to 2.5) | 0.68 | 1.1 (− 2.7 to 5.0) | 0.56 | − 0.4 (− 3.6 to 2.9) | 0.83 | −1.5 (− 3.2 to 0.2) | 0.08 |
GSRS-constipation | 1.2 (− 4.4 to 6.9) | 0.67 | 7.0 (−1.6 to 15.6) | 0.11 | −3.6 (− 11.1 to 3.8) | 0.34 | −10.6 (− 22.1 to 0.94) | 0.07 |
GSRS-diarrhoea | 6.6 (1.3 to 11.8) | 0.02 | 13.6 (6.2 to 20.9) | < 0.001 | −0.4 (− 7.7 to 6.9) | 0.91 | 14.0 (3.5 to 24.4) | 0.009 |
HbA1c (%) | 9.7 (1.1 to 18.3) | 0.03 | 16.1 (5.9 to 26.3) | 0.002 | −6.0 (−20.9 to 8.9) | 0.43 | −22.1 (−4.2 to −40.0) | 0.016 |
Plasma glucose (mmol/L) | 3.5 (1.2 to 5.9) | 0.004 | 5.1 (2.4 to 7.7) | < 0.001 | −2.6 (−7.9 to 2.7) | 0.34 | −7.6 (−1.7 to 13.6) | 0.012 |
C-reactive protein (mg/L) | 0.8 (−0.5 to 2.1) | 0.22 | 1.2 (−0.4 to 2.9) | 0.15 | 0.2 (−1.9 to 2.3) | 0.88 | −1.1 (−3.7 to 1.6) | 0.43 |
Gamma-GT (U/L) | 0.28 (0.09 to 0.47) | 0.004 | 0.36 (0.15 to 0.58) | 0.001 | −0.02 (− 0.40 to 0.37) | 0.93 | 0.38 (− 0.06 to 0.82) | 0.09 |