Evaluation of the role of B7-H3 haplotype in association with impaired B7-H3 expression and protection against type 1 diabetes in Chinese Han population

Table 2 Four markers of the B7-H3 gene investigated in Han Chinese patients with T1D disease

	dbSNP	chr position and	Frequency(%)				Frequency(%)			HWE
	dbSNP	mRNA position	Allele			P	Genotype			P
SNP1	rs7173448	73,994,806/524		C	T		C/C	C/T	T/T
		C → T	Cases	0.91	0.09		0.85	0.13	0.02	0.16
			Controls	0.82	0.18	0.0064	0.66	0.31	0.03
SNP2	rs7173476	3,994,847/565		C	A		C/C	C/A	A/A
		C → A	Cases	0.91	0.09		0.85	0.13	0.02	0.16
			Controls	0.82	0.18	0.0064	0.66	0.31	0.03
SNP3	–	73,996,569/1359		A	C		A/A	A/C	C/C
		A → C	Cases	0.91	0.09		0.85	0.13	0.02	0.16
			Controls	0.82	0.18	0.0064	0.66	0.31	0.03
SNP4	rs145827704	73,996,577/1367		C	T		C/C	C/T	T/T
		C → T	Cases	0.91	0.09		0.85	0.13	0.02	0.16
			Controls	0.82	0.18	0.0064	0.66	0.31	0.03

ISSN: 1472-6823