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Table 2 Baseline characteristics of subgroups of non-PCOS and PCOS without HA participants

From: PCOS without hyperandrogenism is associated with higher plasma Trimethylamine N-oxide levels

 ControlPCOS-N
BMI < 24BMI ≥ 24BMI < 24BMI ≥ 24
n11121116
Age (years)27.00 (26.00–29.00)26.50 (22.5–28.75)26.00 (24.00–29.00)27.00 (25.50–29.75)
BMI (kg/m2)21.23 (19.35–22.20)27.39 (25.99–28.90)a20.83 (19.20–22.58)b27.19 (24.65–29.59) ac
LH (IU/L)5.21 (4.21–5.63)6.16 (5.00–11.13)8.72 (6.67–15.23)11.33 (7.26–20.24)a
FSH (IU/L)6.96 (5.32–9.36)6.28 (5.97–7.41)5.43 (3.20–8.51)5.82 (3.60–7.17)
LH/FSH0.79 (0.60–0.91)1.01 (0.82–1.54)1.62 (1.33–2.42)a1.90 (1.36–2.87)ab
P (nmol/L)0.70 (0.60–0.91)0.52 (0.37–0.98)0.77 (0.45–1.75)0.51 (0.38–0.88)
E2 (pmol/L)130.80 (94.00–175.40)168.65 (132.85–381.08)230.00 (120.40–585.30)159.70 (108.4–235.35)
T (nmol/L)1.10 (0.61–1.37)0.90 (0.76–1.59)1.37 (1.09–1.56)1.18 (0.95–1.40)
FT (pmol/L)7.42 (5.95–9.93)6.92 (6.51–10.11)6.01 (4.93–10.45)9.99 (6.71–13.34)
FBG (mmol/L)5.60 (5.20–6.00)5.70 (5.05–5.98)5.80 (5.60–6.30)b6.10 (5.70–6.58)
FINS (μIU/ml)8.99 (7.40–10.80)16.88 (12.53–20.51)a12.78 (8.98–14.65)15.79 (11.95–30.87)a
HOMA-IR2.38 (1.91–2.59)3.98 (3.00–5.22)a3.57 (2.27–3.65)4.16 (3.15–8.99)a
Cr (μmol/L)64.40 (59.00–66.20)64.30 (61.08–66.50)59.70 (56.20–69.00)64.95 (63.50–67.28)
CRP (mg/L)1.02 (0.46–2.61)1.56 (1.06–3.16)0.84 (0.20–1.37)2.15 (1.53–5.58)ac
CHOL (mmol/L)4.80 (4.01–5.34)4.75 (4.31–5.11)4.41 (3.96–4.81)5.11 (4.69–6.01)
TG (mmol/L)1.03 (0.90–1.24)1.01 (0.80–1.86)0.81 (0.60–1.43)1.53 (1.13–2.24)
ALT (U/L)13.00 (8.00–19.00)24.00 (18.25–35.00)15.00 (10.00–21.00)28.00 (15.75–36.25)ac
AST (U/L)16.00 (13.00–17.00)20.00 (16.25–28.00)a17.00 (15.00–22.00)20.00 (16.50–21.75)
HDL (mmol/L)1.42 (1.27–1.59)1.40 (1.23–1.59)1.63 (1.31–1.85)1.25 (1.13–1.51)
LDL (mmol/L)2.72 (2.28–3.49)2.77 (2.26–3.38)2.44 (1.90–3.01)2.85 (2.52–3.39)
sdLDL (mmol/L)0.87 (0.73–1.06)0.84 (0.60–1.17)0.77 (0.57–0.95)1.18 (0.76–1.54)
APOA (g/L)1.40 (1.21–1.64)1.35 (1.26–1.63)1.46 (1.33–1.57)1.38 (1.30–1.53)
APOB (g/L)0.73 (0.64–0.80)0.72 (0.62–0.83)0.65 (0.54–0.71)0.78 (0.64–0.87)
  1. Data are presented as median (interquartile range). aP < 0.05 versus control-normal weight participants, bP < 0.05 versus control-obese weight participants, cP < 0.05 versus PCOS-normal weight participants. BMI Body mass index, LH Luteinizing hormone, FSH Follicle-stimulating hormone, P Progesterone, E2 Estradiol, T Testosterone, FT Free testosterone, FBG Fasting blood glucose, FINS Fasting plasma insulin, HOMA-IR Homeostasis model assessment insulin resistance index, Cr Creatinine, CRP C-reactive protein, CHOL Cholesterol, TG Triglyceride, ALT Alanine transaminase, AST Aspartate aminotransferase, LDL Low-density lipoprotein, HDL High-density lipoprotein, sdLDL Small dense LDL, APOA Apolipoprotein A, APOB apolipoprotein B