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Table 1 Baseline characteristics of non-PCOS and PCOS without HA participants

From: PCOS without hyperandrogenism is associated with higher plasma Trimethylamine N-oxide levels

 ControlPCOS-NP-Value
n2327 
Age (years)27.00 (24.00–29.00)27.00 (25.00–29.00)0.746
BMI (kg/m2)24.77 (21.23–27.48)24.46 (21.09–28.60)0.853
LH (IU/L)5.35 (4.21–7.01)9.80 (7.06–16.57)0.001*
FSH (IU/L)6.33 (5.87–7.78)5.77 (3.22–7.34)0.056
LH/FSH0.83 (0.67–1.25)1.77 (1.35–2.77)0.0001**
P (nmol/L)0.63 (0.36–0.99)0.57 (0.41–1.05)0.619
E2 (pmol/L)149.30 (113.60–204.30)189.70 (114.70–274.60)0.490
T (nmol/L)1.10 (0.75–1.50)1.22 (1.08–1.44)0.164
FT (pmol/L)7.18 (6.47–10.03)8.17 (6.01–11.39)0.697
FBG (mmol/L)5.60 (5.20–6.00)6.00 (5.60–6.50)0.009*
FINS (μIU/ml)11.90 (8.91–17.02)14.62 (11.00–19.62)0.158
HOMA-IR2.82 (2.16–4.35)3.65 (2.98–5.58)0.044
Cr (μmol/L)64.40 (59.00–66.50)63.90 (59.10–67.30)0.884
CRP (mg/L)1.16 (0.78–2.63)1.52 (0.82–3.40)0.683
CHOL (mmol/L)4.80 (4.27–5.13)4.80 (4.21–5.61)0.633
TG (mmol/L)1.03 (0.86–1.49)1.39 (0.74–2.02)0.640
ALT (U/L)19.00 (11.00–27.00)21.00 (13.00–32.00)0.465
AST (U/L)17.00 (16.00–22.00)19.00 (16.00–22.00)0.464
HDL (mmol/L)1.42 (1.27–1.59)1.32 (1.20–1.64)0.823
LDL (mmol/L)2.72 (2.28–3.49)2.60 (2.00–3.21)0.533
sdLDL (mmol/L)0.87 (0.71–1.06)0.95 (0.67–1.34)0.546
APOA (g/L)1.35 (1.25–1.64)1.40 (1.30–1.53)0.533
APOB (g/L)0.73 (0.63–0.80)0.69 (0.63–0.83)0.853
  1. Data are presented as median (interquartile range). (*) represents significant difference between groups, p < 0.01; (**) represents significant difference between groups, p < 0.0001. BMI Body mass index, LH luteinizing hormone, FSH Follicle-stimulating hormone, P Progesterone, E2 Estradiol, T Testosterone, FT Free testosterone, FBG Fasting blood glucose, FINS Fasting plasma insulin, HOMA-IR Homeostasis model assessment insulin resistance index, Cr Creatinine, CRP C-reactive protein, CHOL Cholesterol, TG Triglyceride, ALT Alanine transaminase, AST Aspartate aminotransferase, LDL Low-density lipoprotein, HDL High-density lipoprotein, sdLDL Small dense LDL, APOA Apolipoprotein A, APOB Apolipoprotein B