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Table 1 Baseline characteristics of non-PCOS and PCOS without HA participants

From: PCOS without hyperandrogenism is associated with higher plasma Trimethylamine N-oxide levels

 

Control

PCOS-N

P-Value

n

23

27

 

Age (years)

27.00 (24.00–29.00)

27.00 (25.00–29.00)

0.746

BMI (kg/m2)

24.77 (21.23–27.48)

24.46 (21.09–28.60)

0.853

LH (IU/L)

5.35 (4.21–7.01)

9.80 (7.06–16.57)

0.001*

FSH (IU/L)

6.33 (5.87–7.78)

5.77 (3.22–7.34)

0.056

LH/FSH

0.83 (0.67–1.25)

1.77 (1.35–2.77)

0.0001**

P (nmol/L)

0.63 (0.36–0.99)

0.57 (0.41–1.05)

0.619

E2 (pmol/L)

149.30 (113.60–204.30)

189.70 (114.70–274.60)

0.490

T (nmol/L)

1.10 (0.75–1.50)

1.22 (1.08–1.44)

0.164

FT (pmol/L)

7.18 (6.47–10.03)

8.17 (6.01–11.39)

0.697

FBG (mmol/L)

5.60 (5.20–6.00)

6.00 (5.60–6.50)

0.009*

FINS (μIU/ml)

11.90 (8.91–17.02)

14.62 (11.00–19.62)

0.158

HOMA-IR

2.82 (2.16–4.35)

3.65 (2.98–5.58)

0.044

Cr (μmol/L)

64.40 (59.00–66.50)

63.90 (59.10–67.30)

0.884

CRP (mg/L)

1.16 (0.78–2.63)

1.52 (0.82–3.40)

0.683

CHOL (mmol/L)

4.80 (4.27–5.13)

4.80 (4.21–5.61)

0.633

TG (mmol/L)

1.03 (0.86–1.49)

1.39 (0.74–2.02)

0.640

ALT (U/L)

19.00 (11.00–27.00)

21.00 (13.00–32.00)

0.465

AST (U/L)

17.00 (16.00–22.00)

19.00 (16.00–22.00)

0.464

HDL (mmol/L)

1.42 (1.27–1.59)

1.32 (1.20–1.64)

0.823

LDL (mmol/L)

2.72 (2.28–3.49)

2.60 (2.00–3.21)

0.533

sdLDL (mmol/L)

0.87 (0.71–1.06)

0.95 (0.67–1.34)

0.546

APOA (g/L)

1.35 (1.25–1.64)

1.40 (1.30–1.53)

0.533

APOB (g/L)

0.73 (0.63–0.80)

0.69 (0.63–0.83)

0.853

  1. Data are presented as median (interquartile range). (*) represents significant difference between groups, p < 0.01; (**) represents significant difference between groups, p < 0.0001. BMI Body mass index, LH luteinizing hormone, FSH Follicle-stimulating hormone, P Progesterone, E2 Estradiol, T Testosterone, FT Free testosterone, FBG Fasting blood glucose, FINS Fasting plasma insulin, HOMA-IR Homeostasis model assessment insulin resistance index, Cr Creatinine, CRP C-reactive protein, CHOL Cholesterol, TG Triglyceride, ALT Alanine transaminase, AST Aspartate aminotransferase, LDL Low-density lipoprotein, HDL High-density lipoprotein, sdLDL Small dense LDL, APOA Apolipoprotein A, APOB Apolipoprotein B