TY - JOUR AU - Morales, Jessikah AU - Glantz, Namino AU - Larez, Arianna AU - Bevier, Wendy AU - Conneely, Mary AU - Fan, Ludi AU - Reed, Beverly AU - Alatorre, Carlos AU - Paczkowski, Rosirene AU - Ahmed, Tamim AU - Mackenzie, Andrew AU - Duncan, Ian AU - Kerr, David PY - 2020 DA - 2020/01/06 TI - Understanding the impact of five major determinants of health (genetics, biology, behavior, psychology, society/environment) on type 2 diabetes in U.S. Hispanic/Latino families: Mil Familias - a cohort study JO - BMC Endocrine Disorders SP - 4 VL - 20 IS - 1 AB - In the United States (U.S.), the prevalence of both diagnosed and undiagnosed type 2 diabetes (T2D) is nearly twice as high among Mexican-origin Hispanic/Latino adults compared to non-Hispanic Whites. Rates of diabetes-related complications, e.g., acute stroke and end-stage renal disease, are also higher among Hispanic/Latino adults compared to their non-Hispanic/Latino White counterparts. Beyond genetic and biological factors, it is now recognized that sociocultural influences are also important factors in determining risk for T2D and the associated complications. These influences include ethnicity, acculturation, residence, education, and economic status. The primary objective of this study is to determine the influence of the 5 major determinants of human health (genetics, biology, behavior, psychology, society/environment) on the burden of T2D for Latino families. To achieve this objective, Mil Familias (www.milfamilias.sansum.org/) is establishing an observational cohort of 1000 Latino families, with at least one family member living with T2D. SN - 1472-6823 UR - https://doi.org/10.1186/s12902-019-0483-z DO - 10.1186/s12902-019-0483-z ID - Morales2020 ER -