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Table 4 Total testosterone, fasting insulin, and homeostasis model assessment of insulin resistance according to the groups and the genotypes of vitamin D receptor gene polymorphisms

From: Vitamin D receptor and binding protein polymorphisms in women with polycystic ovary syndrome: a case control study

VariablesGroupsVDR polymorphismsGenotypesAdjusted mean95% CIP for groupP for genotypeP for interaction
TTControlrs10735810GG45.8844.09~47.67< 0.0010.0240.043
AG46.0744.51~47.64
AA45.6443.07~48.22
PCOSGG73.6771.01~76.32
AG79.1176.80~81.42
AA75.5171.51~79.51
Fasting insulinaControlrs10875695AC1.411.04~1.91< 0.0010.0870.011
CC1.060.74~1.51
AA3.121.77~5.50
PCOSAC5.744.46~7.39
CC7.335.51~9.76
AA6.073.91~9.41
HOMA-IRaControlrs10875695AC0.300.22~0.41< 0.0010.1000.009
CC0.220.16~0.32
AA0.660.38~1.18
PCOSAC1.220.95~1.57
CC1.551.17~2.07
AA1.250.81~1.95
  1. Adjusted for age and body mass index
  2. VDR vitamin D receptor, CI confidence interval, TT total testosterone, PCOS polycystic ovary syndrome, HOMA-IR homeostasis model assessment of insulin resistance
  3. aLogarithmic transformations were applied for analyses and adjusted means are geometric means after adjustment for age and body mass index