Skip to main content

Advertisement

Table 1 List of key risk factors implicated in the pathogenesis of type 2 diabetes mellitus (T2DM)

From: Sociodemographic and lifestyle-related risk factors for identifying vulnerable groups for type 2 diabetes: a narrative review with emphasis on data from Europe

Key risk factors implicated in the pathogenesis of type 2 diabetes mellitus (T2DM)
▪ Increased body weight - overweight or obesity (body mass index, BMI, ≥25 kg/m2 for Caucasian adults)
▪ Increased abdominal/visceral adiposity - central/android obesity, increased waist circumference independent of BMI
▪ Other metabolic syndrome components (e.g. hypertriglyceridemia, low HDL-cholesterol plasma levels, hypertension)
▪ Unhealthy eating/dietary habits (e.g. high consumption of processed red meat, sugar-sweetened beverages and alcohol, and/or low consumption of fruits, vegetables, high-fiber and whole grain foods)
▪ Sedentary lifestyle - decreased physical activity
▪ Cigarette/tobacco smoking
▪ Aging (older age)
▪ Race/Ethnicity (non-white ethnic background/ancestry)
▪ T2DM family history (particularly with first degree relatives and with earlier age of onset)
▪ Genetic predisposition/factors
▪ Gestational diabetes mellitus history
▪ Low socioeconomic status, deprivation
▪ Stress, anxiety and depression
▪ Certain medications (e.g. certain statins and beta-blockers)