Cost-effectiveness of insulin degludec versus insulin glargine U100 in adults with type 1 and type 2 diabetes mellitus in Bulgaria

Table 1 Basal and bolus insulin use

Treatment group	Observed glargine U100 (units/day)	Dose ratio (degludec/glargine U100)	Calculated degludec (units/day)
T1DM_B/B, total dose		0.88*
Basal insulin	28.11	0.87*	24.46
Bolus insulin	37.13	0.88*	32.67
T2DM_BOT, total dose		0.90*
Basal insulin	28.11	0.90*	25.30
Bolus insulin	Not relevant	Not relevant	Not relevant
T2DM_B/B, total dose		Not significant
Basal insulin	28.11	1.08*	30.36
Bolus insulin	37.13	Not significant	37.13

Abbreviations: B/B Basal-bolus, BOT Basal oral therapy, T1DM Type 1 diabetes mellitus, T2DM Type 2 diabetes mellitus
* p < 0.05; NS Non-significant; in the case of non-significant results, a relative rate of one was used in the calculation

ISSN: 1472-6823