Table 3 Relationships between PD-NLR and clinicopathological characteristics in patients with surgically resected neuroendocrine tumors in the head of the pancreas
Variable | No. of cases | PD-NLR | P | ||
|---|---|---|---|---|---|
(n = 64) | 0 (n = 37, %) | 1 (n = 19, %) | 2 (n = 8, %) | ||
Age (years) | |||||
≤ 60 | 44 | 27 (73) | 13 (68.4) | 4 (50) | 0.245 |
> 60 | 20 | 10 (27) | 6 (31.6) | 4 (50) | |
Gender | |||||
Female | 35 | 22 (59.5) | 8 (42.1) | 5 (62.5) | 0.687 |
Male | 29 | 15 (40.5) | 11 (57.9) | 3 (37.5) | |
tumor size (cm) | |||||
≤ 2.5 | 33 | 24 (64.9) | 8 (42.1) | 1 (12.5) | 0.005 |
> 2.5 | 31 | 13 (35.1) | 11 (57.9) | 7 (87.5) | |
Symptoms | |||||
Absent | 20 | 14 (37.8) | 6 (31.6) | 0 | 0.061 |
Present | 44 | 23 (62.2) | 13 (68.4) | 8 (100) | |
T-stage | |||||
T1–2 | 49 | 32 (86.5) | 13 (68.4) | 4 (50) | 0.016 |
T3–4 | 15 | 5 (13.5) | 6 (31.6) | 4 (50) | |
LN metastasis | |||||
Absent | 49 | 34 (91.9) | 13 (68.4) | 2 (25) | < 0.001 |
Present | 15 | 3 (8.1) | 6 (31.6) | 6 (75) | |
Distant metastasis | |||||
Absent | 61 | 37 (100) | 18 (94.7) | 6 (75) | 0.005 |
Present | 3 | 0 | 1 (5.3) | 2 (25) | |
Type of hormone production | |||||
Non-functioning | 48 | 23 (62.2) | 17 (89.5) | 8 (100) | 0.006 |
Functioning | 16 | 14 (37.8) | 2 (10.5) | 0 | |
Perineural invasion | |||||
Absent | 56 | 35 (94.6) | 16 (84.2) | 5 (87.5) | 0.014 |
Present | 8 | 2 (5.4) | 3 (15.8) | 3 (12.5) | |
WHO classification | |||||
Grade 1 | 28 | 25 (67.6) | 3 (15.8) | 0 | < 0.001 |
Grade 2 | 26 | 12 (32.4) | 11 (57.9) | 3 (37.5) | |
Grade 3 | 10 | 0 | 5 (26.3) | 5 (62.5) | |