Skip to main content

Table 2 Variables associated with DFS according to the Cox proportional hazards regression model

From: Clinical significance of the preoperative main pancreatic duct dilation and neutrophil-to-lymphocyte ratio in pancreatic neuroendocrine tumors (PNETs) of the head after curative resection

Variable

Univariate analysis

Multivariate analysis

HR

95% CI

P

HR

95% CI

P

Age (years)

  ≤ 60

Reference

     

  > 60

1.321

0.525–3.324

0.554

   

Gender

 Female

Reference

     

 Male

1.481

0.613–3.577

0.382

   

tumor size (cm)

  ≤ 2.5

Reference

  

Reference

  

  > 2.5

7.449

2.177–25.491

0.001

4.109

1.054–16.023

0.042

Symptoms

 Absent

Reference

  

Reference

  

 Present

4.935

1.143–21.302

0.032

NA

NA

0.185

PD-NLR

 0

Reference

     

 1

14.132

3.083–64.774

0.001

7.356

1.495–36.194

0.014

 2

41.928

8.731–201.359

<  0.001

15.144

2.762–83.020

0.002

Type of hormone production

 Functioning

Reference

     

 Non-functioning

34.588

0.572–2090.521

0.09

   

T-stage

 T1–2

Reference

  

Reference

  

 T3–4

2.539

1.034–6.234

0.042

NA

NA

0.222

LN metastasis

 Absent

Reference

  

Reference

  

 Present

5.789

2.368–14.152

<  0.001

NA

NA

0.394

Distant metastasis

 Absent

Reference

  

Reference

  

 Present

17.364

4.136–72.889

<  0.001

NA

NA

0.271

Perineural invasion

 Absent

Reference

  

Reference

  

 Present

4.419

1.681–11.620

0.003

NA

NA

0.287

WHO classification

 Grade 1–2

Reference

     

 Grade 3

14.287

5.321–38.358

<  0.001

6.595

1.846–23.565

0.004

  1. DFS Disease-free survival, PD Main pancreatic duct dilation, NLR Neutrophil-to-lymphocyte ratio, LN Lymph node. P-values < 0.05, marked in bold font, indicate statistical significance
Back to article page

BMC Endocrine Disorders

ISSN: 1472-6823

Contact us