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Table 1 Variables associated with OS according to the Cox proportional hazards regression model

From: Clinical significance of the preoperative main pancreatic duct dilation and neutrophil-to-lymphocyte ratio in pancreatic neuroendocrine tumors (PNETs) of the head after curative resection

Variable

Univariate analysis

Multivariate analysis

HR

95% CI

P

HR

95% CI

P

Age (years)

  ≤ 60

Reference

     

  > 60

2.074

0.721–5.966

0.176

   

Gender

 Female

Reference

     

 Male

1.064

0.385–2.939

0.905

   

Tumor size (cm)

  ≤ 2.5

Reference

  

Reference

  

  > 2.5

7.336

1.655–32.514

0.009

NA

NA

0.249

Symptoms

 Absent

Reference

     

 Present

3.223

0.727–14.292

0.123

   

PD-NLR

 0

Reference

  

Reference

  

 1

20.055

2.444–164.556

0.005

16.159

1.902–137.304

0.011

 2

56.819

6.874–469.680

<  0.001

32.737

3.561–300.966

0.002

Type of hormone production

 Functioning

Reference

     

 Non-functioning

33.418

0.265–4211.462

0.155

   

T-stage

 T1–2

Reference

  

Reference

  

 T3–4

3.602

1.303–9.953

0.013

NA

NA

0.567

LN metastasis

 Absent

Reference

  

Reference

  

 Present

6.896

2.359–20.157

<  0.001

NA

NA

0.608

Distant metastasis

 Absent

Reference

     

 Present

3.438

0.426–27.722

0.246

   

Perineural invasion

 Absent

Reference

  

Reference

  

 Present

6.453

2.247–18.537

0.001

NA

NA

0.118

WHO classification

 Grade 1–2

Reference

  

Reference

  

 Grade 3

19.191

4.735–77.784

<  0.001

5.222

1.227–22.218

0.025

  1. OS Overall survival, PD Main pancreatic duct dilation, NLR Neutrophil-to-lymphocyte ratio, LN Lymph node. P-values < 0.05, marked in bold font, indicate statistical significance
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BMC Endocrine Disorders

ISSN: 1472-6823

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