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Table 4 Demographic and metabolic characteristics of 9059 participants with OGTT glucose peak at 30 min, 60 min versus 120 min

From: The shape of the glucose response curve during an oral glucose tolerance test heralds β–cell function in a large Chinese population

 

OGTT glucose peak at 30 min

(n = 4599)

OGTT glucose peak at 60 min

(n = 3912)

OGTT glucose peak at 120 min

(n = 548)

P

Age (years)

35.8 ± 12.8

40.1 ± 13.6

44.9 ± 14.9

<0.001

Sex (male/female), n%

974 (21.2)/3625 (78.8)

1178 (30.1)/2734 (69.9)

167 (30.5)/381 (69.5)

<0.001

FBG(mmol/L)

5.2 ± 0.6

5.7 ± 1.1

6.6 ± 2.0

<0.001

30 min GLU(mmol/L)

8.8 ± 1.6

9.8 ± 2.1

10.6 ± 3.0

<0.001

2 h GLU(mmol/L)

6.3 ± 1.5

8.9 ± 2.8

14.4 ± 4.3

<0.001

FINS

13.6 ± 7.7

15.6 ± 9.2

16.5 ± 10.3

<0.001

30 min INS

121.8 ± 63.6

82.0 ± 50.1

62.6 ± 48.3

<0.001

2 h INS

85.9 ± 58.8

121.5 ± 68.9

116.0 ± 73.2

<0.001

Glycemic status(%)

 NGT(%)

3749 (81.5)

1386 (35.4)

21 (3.8)

 

 IFG/IGT/IFG + IGT(%)

766 (16.7)

1693 (43.3)

109 (19.9)

< 0.001

 DM(%)

84 (1.8)

833 (21.3)

418 (76.3)

 

Glucose AUC (mg·dL −1· h −1)

1202.6 ± 212.3

1609.3 ± 385.4

2163.9 ± 643.5

<0.001

Insulin AUC(mg·dL −1· h − 1)

15,048.7 ± 7705.2

17,313.6 ± 8561.2

14,668.6 ± 8865.8

<0.001

HOMAIR

3.2 ± 1.9

4.1 ± 2.8

4.9 ± 3.9

<0.001

Matsuda Index

3.4 ± 2.1

2.6 ± 1.7

2.8 ± 2.1

<0.001

Insulinogenic index

36.1 ± 30.0

18.8 ± 16.2

15.0 ± 20.9

<0.001

Disposition index

15.6 ± 16.2

11.0 ± 12.4

8.6 ± 12.6

<0.001

  1. Values are reported as the mean ± SD or n (%). FBG fasting blood glucose, 30 min GLU glucose at 30 min, 2 h GLU glucose at 120 min, FINS fasting insulin, 30 min INS insulin at 30 min, 2 h INS insulin at 1200 min, NGT normal glucose tolerance, IFG impaired fasting glucose, IGT impaired glucose tolerance, DM diabetes mellitus, AUC area under the curve