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Table 3 Demographic and metabolic characteristics of 1150 participants with OGTT glucose nadir at 60 min versus at 120 min

From: The shape of the glucose response curve during an oral glucose tolerance test heralds β–cell function in a large Chinese population

 

OGTT glucose nadir at 60 min

(n = 688)

OGTT glucose nadir at 120 min

(n = 462)

P

Age (years)

35.5 ± 13.2

35.3 ± 13.8

0.824

Sex (male/female), n%

119 (17.3)/569 (82.7)

100 (21.6)/362 (78.4)

0.066

FBG (mmol/L)

5.2 ± 0.6

5.2 ± 0.6

0.069

30 min GLU(mmol/L)

8.2 ± 1.6

8.5 ± 1.6

0.004

2 h GLU(mmol/L)

7.1 ± 2.0

5.2 ± 1.6

<0.001

FINS

13.5 ± 7.4

13.4 ± 8.6

0.743

30 min INS

137.7 ± 67.5

102.3 ± 60.6

<0.001

2 h INS

92.6 ± 61.3

53.2 ± 42.3

<0.001

Glycemic status(%)

 NGT(%)

489 (71.1)

414 (89.6)

 

 IFG/IGT/IFG + IGT(%)

167 (24.3)

39 (8.4)

< 0.001

 DM(%)

32 (4.7)

9 (1.9)

 

Glucose AUC (mg·dL −1· h −1)

1175.3 ± 267.0

1190.0 ± 243.4

0.342

Insulin AUC(mg·dL − 1· h − 1)

14,349.1 ± 7572.7

13,402.2 ± 7358.6

0.036

HOMAIR

3.1 ± 1.8

3.1 ± 2.2

0.957

Matsuda Index

3.8 ± 2.5

3.8 ± 2.4

0.670

Insulinogenic index

49.7 ± 40.8

32.7 ± 29.7

<0.001

Disposition index

18.8 ± 19.0

13.1 ± 15.3

<0.001

  1. Values are reported as the mean ± SD or n (%). FBG fasting blood glucose, 30 min GLU glucose at 30 min, 2 h GLU glucose at 120 min, FINS fasting insulin, 30 min INS insulin at 30 min, 2 h INS insulin at 1200 min, NGT normal glucose tolerance, IFG impaired fasting glucose, IGT impaired glucose tolerance, DM diabetes mellitus, AUC area under the curve