Table 1 Demographic and metabolic characteristics of 9059 participants with monophasic versus multiphasic OGTT glucose response curve and 1150 participants with biphasic versus triphasic
Variables | Monophasic group (n = 7909) | Multiphasic group (n = 1150) | P value | Biphasic group (n = 548) | Triphasic group (n = 602) | P value |
|---|---|---|---|---|---|---|
Age (years) | 38.6 ± 13.6 | 35.4 ± 13.5 | < 0.001 | 35.1 ± 13.7 | 35.8 ± 13.2 | 0.391 |
Sex (male/female), n% | 2100 (26.6)/5809 (73.4) | 219 (19.0)/931 (81.0) | < 0.001 | 106 (19.3)/442 (80.7) | 113 (18.8)/489 (81.2) | 0.805 |
FBG (mmol/L) | 5.6 ± 13.5 | 5.2 ± 0.6 | < 0.001 | 5.2 ± 0.6 | 5.2 ± 0.6 | 0.189 |
30 min GLU (mmol/L) | 9.5 ± 2.0 | 8.3 ± 1.6 | < 0.001 | 8.4 ± 1.6 | 8.2 ± 1.6 | <0.001 |
2 h GLU (mmol/L) | 8.2 ± 3.2 | 6.3 ± 2.0 | < 0.001 | 5.4 ± 1.8 | 7.2 ± 1.9 | <0.001 |
FINS | 14.8 ± 8.7 | 13.5 ± 7.9 | < 0.001 | 13.2 ± 8.4 | 13.7 ± 7.5 | 0.328 |
30 min INS | 97.7 ± 59.6 | 123.5 ± 67.1 | < 0.001 | 105.6 ± 62.0 | 139.7 ± 67.5 | <0.001 |
2 h INS | 106.9 ± 66.9 | 76.8 ± 57.8 | < 0.001 | 54.7 ± 43.2 | 96.8 ± 62.0 | <0.001 |
Glycemic status(%) | ||||||
NGT | 4253 (53.8) | 903 (78.5) | 486 (88.7) | 417 (69.3) | ||
IFG/IGT/IFG + IGT | 2362 (29.9) | 206 (17.9) | < 0.001 | 50 (9.1) | 156 (25.9) | <0.001 |
DM | 1294 (16.3) | 41 (3.6) | 12 (2.2) | 29 (4.8) | ||
Glucose AUC (mg·dL −1· h −1) | 1473.5 ± 437.1 | 1181.2 ± 257.8 | < 0.001 | 1180.0 ± 259.7 | 1182.4 ± 256.2 | 0.876 |
Insulin AUC (mg·dL −1· h − 1) | 16,299.7 ± 8297.5 | 13,968.7 ± 7498.6 | < 0.001 | 13,182.2 ± 7277.7 | 14,684.7 ± 7629.9 | 0.001 |
HOMA-IR | 3.8 ± 2.6 | 3.1 ± 2.0 | < 0.001 | 3.1 ± 2.1 | 3.2 ± 1.8 | 0.595 |
Matsuda Index | 2.9 ± 1.9 | 3.8 ± 2.5 | < 0.001 | 4.0 ± 2.7 | 3.6 ± 2.3 | 0.018 |
Insulinogenic index | 25.1 ± 23.0 | 42.9 ± 37.7 | < 0.001 | 36.0 ± 35.9 | 49.1 ± 38.2 | <0.001 |
Disposition index | 12.7 ± 14.1 | 16.6 ± 17.8 | < 0.001 | 13.7 ± 15.4 | 19.2 ± 19.4 | <0.001 |