Skip to main content

Table 3 Basal and stimulated ACTH levels in response to an insulin tolerance test (ITT) in athletes (ATL) and non-physically active control subjects (NPAC)

From: Enhancement of hypothalamic-pituitary activity in male athletes: evidence of a novel hormonal mechanism of physical conditioning

Hormone ATL (n = 25) NPAC (n = 12) P-value (ATL × NPAC)
ACTH (pg/mL) (median; 95% CI)
 Basal 18.7 (6.5–37.8) 21.4 (8.7–37.8) ns
 During hypoglycemia 57.8 (7.3–229.5) 29.5 (14.8–191.7) ns
 P-value of Δ ACTH (x basal) 0.0001 NS  
 30 Minutes after hypoglycemia 59.9 (22.1–195.7) 51.4 (22.7–137.5) ns
 P-value of Δ ACTH (x basal) <0.0001 0.001  
  1. Abbreviations: ACTH adrenocorticotropic hormone, CI confidence interval, ns non significant