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Table 3 Basal and stimulated ACTH levels in response to an insulin tolerance test (ITT) in athletes (ATL) and non-physically active control subjects (NPAC)

From: Enhancement of hypothalamic-pituitary activity in male athletes: evidence of a novel hormonal mechanism of physical conditioning

Hormone

ATL (n = 25)

NPAC (n = 12)

P-value (ATL × NPAC)

ACTH (pg/mL) (median; 95% CI)

 Basal

18.7 (6.5–37.8)

21.4 (8.7–37.8)

ns

 During hypoglycemia

57.8 (7.3–229.5)

29.5 (14.8–191.7)

ns

 P-value of Δ ACTH (x basal)

0.0001

NS

 

 30 Minutes after hypoglycemia

59.9 (22.1–195.7)

51.4 (22.7–137.5)

ns

 P-value of Δ ACTH (x basal)

<0.0001

0.001

 
  1. Abbreviations: ACTH adrenocorticotropic hormone, CI confidence interval, ns non significant