Table 1 Main clinical and laboratory parameters at the different visits

Time lapse from Visit 1

0

1 month

3 months

5 months

32 months

Demographics: woman

28 yrs. old

31 yrs. old

BMI (kg/m²)

22,5

22,5

22,5

22,5

23,0

DM treatment

Insulin degludec / Insulin aspart

same

same

same

Towards CSII

HbA1c

14,9%

NA^a

9,8%

11%

8%

Creatinine / urea^b

0,69 / 34

NA^a

0,7 / 39

1,0 / 47

But recent nephrotic syndrome

WBC (/μL)

6900

NA^a

7210

7700

8220

ESR (mm/1 h)

56

NA^a

42

26

40

CRP^c

16,4

NA^a

11,2

4,37

13,2

Retinopathy

+

+

+

+

+++

Neuropathy, peripheral^d

+

+

+

+

+

Neuropathy, autonomic

+

++

++

++

++

Ankle oedema

+++

+

+

++

++

X-ray findings

+

+

++

+++