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Table 3 Results of the generalized estimation equation models showing the effect of 12 and 24-week of energy restricted low glycemic index diet on anthropometric and metabolic parameters in women with polycystic ovary syndrome compared to eumenorrheic non hirsute controls

From: Does a restricted energy low glycemic index diet have a different effect on overweight women with or without polycystic ovary syndrome?

parameters

Variables

Baseline

12 weeks

24 weeks

∆ 24–0 weeks

Within-group P-value¥

Beta Coef.

95% Confidence Interval

Between-group P-value£

Weight (kg)

PCOs

79± 2.30

75.34± 2.30

72.65± 2.40

-6.70 ± 0.56

< 0.001

2.50

(− 2.80, 7.80)

0.53

Controls

76.60 ± 1.53

73.01 ± 1.52

70.40 ± 1.52

-6. 21±0.51

< 0.001

Reference

  

Time

     

-3.25

(− 3.72, − 2.80)

< 0.001

PCOs* Time

     

-. 20

(− 0.90,0.50)

0.57

Controls*Time

     

Reference

  

BMI (kg/m2)

PCOs

31.00 ± 0.95

29.58 ± 0.94

28.54 ± 1.00

-2.62 ± 0. 20

< 0.001

0.24

(− 1.80, 2. 27)

0.81

Controls

30.91 ± 0.52

29.47 ± 0.53

28.42 ± 0.56

-2.50 ± 0. 20

< 0.001

Reference

  

Time

     

−1.19

(−1.33, − 1.05)

< 0.001

PCOs* Time

     

−0.1

(− 0.30, 0. 11)

0.36

Controls*Time

     

Reference

  

WC (cm)

PCOs

95.48± 2.26

91.25± 2.36

88.74± 2.41

-7.10 ± 0.77

< 0.001

1.40

(−3.66, 6.45)

0.58

Controls

94.31 ± 1. 20

90.38 ± 1. 20

87.68 ± 1.26

-6.63 ± 0.62

< 0.001

Reference

  

Time

     

-2.86

(− 3.43, − 2.30)

< 0.001

PCOs* Time

     

− 0.24

(− 1.08, 0.60)

0.57

Controls*Time

     

Reference

  

SBP (mmHg)

PCOs

120.50 ± 1.94

117.57 ± 1.83

119.92± 3.47

−0.63± 3.32

0.67

0.97

(−5.94, 7.89)

0.78

Controls

118.79 ± 1.26

117.15 ± 1.34

117.32 ± 1.51

−1.80 ± 0.52

< 0.001

Reference

  

Time

     

−0.87

(− 2.72,0.98)

0.36

PCOs* Time

     

0.33

(−2.36, 3.02)

0.81

Controls*Time

     

Reference

  

DBP (mmHg)

PCOs

77.18 ± 1.30

76.53 ± 1.17

76.00 ± 1. 12

−1.18 ± 0.65

0.03

−0.02

(−2.86, 2.83)

0.98

Controls

78.25 ± 0.85

78.88 ± 0.81

78.73 ± 0.79

0.41 ± 0. 21

0.05

Reference

  

Time

     

0.37

(0.05,0.69)

0.02

PCOs* Time

     

−0.99

(− 1.46, − 0.52)

< 0.001

Controls*Time

     

Reference

  

FBG (mg/dl)

PCOs

80.86 ± 1.87

82.75 ± 1.62

83. 11±1.97

2.25± 2. 27

0.34

-4.48

(− 10.93, 1.98)

0.17

Controls

85.23 ± 1.69

85.60± 2.35

86.23 ± 1. 21

1.00 ± 1.90

0.61

Reference

  

Time

     

0.51

(−1.41, 2.43)

0.60

PCOs* Time

     

0.49

(−2.40, 3.38)

0.73

Controls*Time

     

Reference

  

Fasting Insulin (mu/L)

PCOs

14.25 ± 1.17

12. 11±1.48

9.45 ± 1. 27

-4.77 ± 1.57

0.001

1.45

(−3.38, 6.28)

0.55

Controls

13.41 ± 1. 20

10.84 ± 1.50

9.64 ± 0.78

-3.77 ± 1.30

0.001

Reference

  

Time

     

−1.88

(− 3.30, − 0.47)

0.009

PCOs* Time

     

− 0.57

(− 2.68, 1.54)

0.59

Controls*Time

     

Reference

  

HOMA_IR

PCOs

2.82 ± 0.24

2.48 ± 0.33

1.96 ± 0.31

− 0.83 ± 0.33

0.001

0.06

(− 0.10, 1. 12)

0.91

Controls

2.82 ± 0.26

2.26 ± 0.34

2.03 ± 0.16

−0.79 ± 0.28

0.001

Reference

  

Time

     

−0.40

(−0.70, − 0.09)

0.01

PCOs* Time

     

−0.05

(− 0.51, 0.41)

0.83

Controls*Time

     

Reference

  
  1. Values are mean ± SE; The generalized estimation equation (GEE) method was used to estimate the effect of 12 and 24-week of energy restricted low glycemic index diet on anthropometric and metabolic parameters in women with polycystic ovary syndrome versus eumenorrheic non hirsute controls
  2. BMI Body mass index, WC Waist circumference, SBP Systolic blood pressure, mmHg Millimeters of mercury, DBP Diastolic blood pressure, mg/dl Milligrams /deciliter, mu/L Milliunits/ liter, FBG Fasting blood glucose, HOMA_IR Homeostatic model assessment
  3. ¥within-group P-value = effect of intervention (24-week of energy restricted low glycemic index diet) on anthropometric and metabolic parameters; £between-group P-value = comparison the effect of intervention (24-week of energy restricted low glycemic index diet) on anthropometric and metabolic parameters in women with polycystic ovary syndrome versus eumenorrheic non hirsute controls
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BMC Endocrine Disorders

ISSN: 1472-6823

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