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Table 3 Results of the generalized estimation equation models showing the effect of 12 and 24-week of energy restricted low glycemic index diet on anthropometric and metabolic parameters in women with polycystic ovary syndrome compared to eumenorrheic non hirsute controls

From: Does a restricted energy low glycemic index diet have a different effect on overweight women with or without polycystic ovary syndrome?

parameters Variables Baseline 12 weeks 24 weeks ∆ 24–0 weeks Within-group P-value¥ Beta Coef. 95% Confidence Interval Between-group P-value£
Weight (kg) PCOs 79± 2.30 75.34± 2.30 72.65± 2.40 -6.70 ± 0.56 < 0.001 2.50 (− 2.80, 7.80) 0.53
Controls 76.60 ± 1.53 73.01 ± 1.52 70.40 ± 1.52 -6. 21±0.51 < 0.001 Reference   
Time       -3.25 (− 3.72, − 2.80) < 0.001
PCOs* Time       -. 20 (− 0.90,0.50) 0.57
Controls*Time       Reference   
BMI (kg/m2) PCOs 31.00 ± 0.95 29.58 ± 0.94 28.54 ± 1.00 -2.62 ± 0. 20 < 0.001 0.24 (− 1.80, 2. 27) 0.81
Controls 30.91 ± 0.52 29.47 ± 0.53 28.42 ± 0.56 -2.50 ± 0. 20 < 0.001 Reference   
Time       −1.19 (−1.33, − 1.05) < 0.001
PCOs* Time       −0.1 (− 0.30, 0. 11) 0.36
Controls*Time       Reference   
WC (cm) PCOs 95.48± 2.26 91.25± 2.36 88.74± 2.41 -7.10 ± 0.77 < 0.001 1.40 (−3.66, 6.45) 0.58
Controls 94.31 ± 1. 20 90.38 ± 1. 20 87.68 ± 1.26 -6.63 ± 0.62 < 0.001 Reference   
Time       -2.86 (− 3.43, − 2.30) < 0.001
PCOs* Time       − 0.24 (− 1.08, 0.60) 0.57
Controls*Time       Reference   
SBP (mmHg) PCOs 120.50 ± 1.94 117.57 ± 1.83 119.92± 3.47 −0.63± 3.32 0.67 0.97 (−5.94, 7.89) 0.78
Controls 118.79 ± 1.26 117.15 ± 1.34 117.32 ± 1.51 −1.80 ± 0.52 < 0.001 Reference   
Time       −0.87 (− 2.72,0.98) 0.36
PCOs* Time       0.33 (−2.36, 3.02) 0.81
Controls*Time       Reference   
DBP (mmHg) PCOs 77.18 ± 1.30 76.53 ± 1.17 76.00 ± 1. 12 −1.18 ± 0.65 0.03 −0.02 (−2.86, 2.83) 0.98
Controls 78.25 ± 0.85 78.88 ± 0.81 78.73 ± 0.79 0.41 ± 0. 21 0.05 Reference   
Time       0.37 (0.05,0.69) 0.02
PCOs* Time       −0.99 (− 1.46, − 0.52) < 0.001
Controls*Time       Reference   
FBG (mg/dl) PCOs 80.86 ± 1.87 82.75 ± 1.62 83. 11±1.97 2.25± 2. 27 0.34 -4.48 (− 10.93, 1.98) 0.17
Controls 85.23 ± 1.69 85.60± 2.35 86.23 ± 1. 21 1.00 ± 1.90 0.61 Reference   
Time       0.51 (−1.41, 2.43) 0.60
PCOs* Time       0.49 (−2.40, 3.38) 0.73
Controls*Time       Reference   
Fasting Insulin (mu/L) PCOs 14.25 ± 1.17 12. 11±1.48 9.45 ± 1. 27 -4.77 ± 1.57 0.001 1.45 (−3.38, 6.28) 0.55
Controls 13.41 ± 1. 20 10.84 ± 1.50 9.64 ± 0.78 -3.77 ± 1.30 0.001 Reference   
Time       −1.88 (− 3.30, − 0.47) 0.009
PCOs* Time       − 0.57 (− 2.68, 1.54) 0.59
Controls*Time       Reference   
HOMA_IR PCOs 2.82 ± 0.24 2.48 ± 0.33 1.96 ± 0.31 − 0.83 ± 0.33 0.001 0.06 (− 0.10, 1. 12) 0.91
Controls 2.82 ± 0.26 2.26 ± 0.34 2.03 ± 0.16 −0.79 ± 0.28 0.001 Reference   
Time       −0.40 (−0.70, − 0.09) 0.01
PCOs* Time       −0.05 (− 0.51, 0.41) 0.83
Controls*Time       Reference   
  1. Values are mean ± SE; The generalized estimation equation (GEE) method was used to estimate the effect of 12 and 24-week of energy restricted low glycemic index diet on anthropometric and metabolic parameters in women with polycystic ovary syndrome versus eumenorrheic non hirsute controls
  2. BMI Body mass index, WC Waist circumference, SBP Systolic blood pressure, mmHg Millimeters of mercury, DBP Diastolic blood pressure, mg/dl Milligrams /deciliter, mu/L Milliunits/ liter, FBG Fasting blood glucose, HOMA_IR Homeostatic model assessment
  3. ¥within-group P-value = effect of intervention (24-week of energy restricted low glycemic index diet) on anthropometric and metabolic parameters; £between-group P-value = comparison the effect of intervention (24-week of energy restricted low glycemic index diet) on anthropometric and metabolic parameters in women with polycystic ovary syndrome versus eumenorrheic non hirsute controls