Variables | Total (N = 147) Median [P25; P75] or n (%) | Profile 1 (n = 16) Median [P25; P75] or n (%) | Profile 2 (n = 14) Median [P25; P75] or n (%) | Profile 3 (n = 23) Median [P25; P75] or n (%) | Profile 4 (n = 29) Median [P25; P75] or n (%) | Profile 5 (n = 28) Median [P25; P75] or n (%) | Profile 6 (n = 37) Median [P25; P75] or n (%) | P-value |
---|---|---|---|---|---|---|---|---|
Characteristics at the time of the last consultation | ||||||||
Age, in years | 80.0 [77.0; 83.0] | 80.5 [76.0; 82.8] | 80.0 [78.0; 84.0] | 77.0 [76.0; 81.0] | 79.0 [76.0; 82.0] | 80.0 [77.0; 83.8] | 81.0 [77.0; 84.0] | 0.545 |
Women | 55 (37.4) | 6 (37.5) | 4 (28.6) | 12 (52.2) | 14 (48.3) | 7 (25.0) | 12 (32.4) | 0.278 |
Family history of diabetes* | 52 (35.4) | 4 (25.0) | 4 (30.8) | 5 (21.7) | 11 (37.9) | 11 (39.3) | 17 (49.6) | 0.348 |
Diabetes duration, in years | 19.0 [12.0; 27.0] | 12.0 [3.3; 14.8] | 15.0 [9.8; 20.3] | 12.0 [5.0; 23.0] | 20.0 [15.5; 28.0] | 23.5 [17.3; 29.0] | 22.0 [14.5; 27.5] | < 0.001 |
Characteristics at the time of HOMA2 | ||||||||
Age at HOMA2, in years | 72.0 [69.0; 76.0] | 73.5 [70.3; 76.5] | 72.0 [70.0; 73.3] | 71.0 [64.0; 76.0] | 71.0 [66.0; 77.0] | 71.0 [68.3; 74.8] | 73.0 [68.0; 77.0] | 0.714 |
BMI, in kg/m2 | 28.3 [25.7; 31.2] | 26.8 [24.9; 29.6] | 26.2 [24.7; 33.1] | 28.0 [25.8; 33.3] | 29.6 [26.6; 34.6] | 27.9 [25.7; 29.6] | 28.2 [25.5; 31.7] | 0.037 |
BMI [18–25[kg/m2 | 33 (22.4) | 4 (25.0) | 5 (35.7) | 3 (13.0) | 8 (27.6) | 9 (32.1) | 4 (10.8) | |
BMI [25–30[kg/m2 | 68 (46.3) | 10 (62.5) | 6 (42.9) | 9 (39.1) | 8 (27.6) | 14 (50.0) | 21 (56.8) | |
BMI ≥30 kg/m2 | 45 (30.6) | 2 (12.5) | 3 (21.4) | 11 (47.8) | 13 (44.8) | 4 (14.3) | 12 (32.4) | |
HbA1c†, in % | 7.1 [6.4; 8.2] | 6.6 [6.0; 7.9] | 5.4 [5.2; 6.6] | 7.0 [6.4; 7.9] | 7.4 [7.1; 8.0] | 6.8 [5.8; 7.2] | 8.4 [7.8; 9.1] | < 0.001 |
Indicators used in latent profile analysis | ||||||||
Age at diagnosis, in years | 62.0 [54.0; 70.0] | 70.5 [63.3; 74.0] | 68.0 [61.0; 70.5] | 64.0 [58.0; 74.0] | 58.0 [54.5; 62.0] | 55.5 [47.8; 67.8] | 61.0 [52.0; 65.0] | < 0.001‡ |
HOMA2%-S, in % | 47.4 [32.1; 73.0] | 50.5 [47.0; 56.4] | 84.1 [58.2; 115.8] | 22.3 [15.1; 31.4] | 35.2 [29.1; 42.9] | 86.3 [74.1; 106.9] | 48.3 [34.3; 40.2] | < 0.001‡ |
HOMA2%-β, in % | 49.3 [32.4; 72.6] | 71.6 [68.1; 76.1] | 66.5 [47.6; 111.1] | 111.6 [95.1; 135.5] | 56.5 [46.8; 65.5] | 39.2 [32.0; 47.9] | 27.3 [21.7; 34.9] | < 0.001‡ |
HOMA2%-βxS, in % | 25.0 [16.0; 37.0] | 36.0 [33.3; 40.5] | 56.0 [52.8; 64.3] | 28.0 [17.0; 34.0] | 20.0 [17.0; 24.0] | 34.5 [28.3; 39.8] | 13.0 [9.0; 16.0] | < 0.001‡ |