The pubertal development mode of Chinese girls with turner syndrome undergoing hormone replacement therapy

BMC Endocrine Disorders

Table 3 The correlation between characteristics and uterine volume, M (P25, P75)

Characteristic	N	M (P25, P75)	N	Uterine volume (max, ml)	R	P
Age (yrs)	71	15.75 (14.96, 16.92)	68	10.99 (5.91, 16.58)	−0.03	0.803
Bone age (yrs)	71	12.50 (12.00, 13.00)			0.154	0.216
Ht before HRT (cm)	71	144.8 0 (140.60, 147.95)			0.254	0.032^*
Wt before HRT (kg)	71	38.50 (35.50, 42.75)			0.218	0.07
FSH age before HRT (yrs)	66	14.50 (13.00, 15.94)			0.134	0.199
FSH level before HRT (IU/L)	66	83.34 (59.65, 107.78)			−0.154	0.235
LH level before HRT (IU/L)	66	16.90 (12.17, 27.795)			−0.223	0.087
FSH level after HRT (IU/L)	42	44.34 (23.057, 61.88)			−0.586	< 0.0001^*
LH level after HRT (IU/L)	42	13.82 (6.767, 16.445)			−0.44	0.005^*
The present estradiol valerate dose (mg)	68	1.25 (1.00, 2.00)			0.499	< 0.0001^*
The HRT time (yrs)	68	2.00 (1.27, 3.94)			0.364	0.002^*

Legend: To detect the possible influencing factors for inducing an optimal uterine development mode in TS girls, we used single-factor analysis and found that the height before HRT, the serum FSH and LH level after HRT and the current dose and duration of estradiol valerate were positively related to the maximum uterine volume

ISSN: 1472-6823