Table 1 Results of initial laboratory tests
Parameters | Parameter Value | Reference interval |
|---|---|---|
Sodium (mmol/L) | 138 | 135–145 |
Potassium (mmol/L) | 5.0 | 3.6–5.1 |
Bicarbonate (mmol/L) | 24 | 22–32 |
eGFR (mL/min) > 90 | 77 | ➢ 90 |
Fasting glucose (mmol/L) | 9.7* | 3.0–7.8 |
HbA1c (%) (mmol/mol) | 7.9 | < 6 (42) |
Albumin (g/L) | 37 | 33–48 |
Alanine aminotransferase (U/L) | 18 | < 45 |
Aspartate aminotransferase (U/L) | 18 | < 45 |
Alkaline phosphatase (U/L) | 66 | 38–126 |
γ-Glutamyl transferase (U/L) | 22 | 0–30 |
Bilirubin (umol/L) | 6 | 0–25 |
Free T4 (pmol/L) | 17.3 | 12–22 |
Free T3 (pmol/L) | 3.5 | 3.1–6.8 |
TSH (mIU/L) | 1.5 | 0.27–4.2 |
Testosterone (nmol/L) | 3.3 | 0–1.7 |
Androgen free index (%) | 12 | 0–4.6 |
DHEAS (umol/L) | 12.9 | 2.1–8.7 |
LH (mIU/ml) | 11.3 | > 30 |
FSH (mIU/L) | 81.7 | 20–90 |
Prolactin (mU/L) | 662 | 102–496 |
IGF1 (nmol/L) | 25 | 3.8–29.8 |
Haemoglobin (g/L) | 143 | 115–165 |
Platelets (× 109/L) | 295 | 150–450 |
Confirmation of Cushing syndrome | ||
0800 cortisol (nmol/L) | 768 | 155–599 |
ACTH (pg/mL) | 35.1 | 7.2–63.3 |
24 h urinary free cortisol (nmol/day) | 413 | (< 166) |
Urine creatinine (24 h) | 10 | (6.0–18) |
Cortisol post 1 mg dexamethasone suppression test (nmol/L) | 122 | 155–599 |
ACTH post 1 mg dexamethasone suppression test (pg/mL) | 18.5 | 7.2–63.3 |
Cortisol post 8 mg dexamethasone suppression test (nmol/L) | 109 | 155–599 |
ACTH post 8 mg dexamethasone suppression test (pg/mL) | 12.6 | 7.2–63.3 |
BIPSS: Central-to-peripheral ACTH maximal ratio (baseline) | 17.4 | ≥2 |
BIPSS: Central-to-peripheral ACTH maximal ratio (5 min after CRH stimulation) | 9.7 | ≥3 |