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Table 1 Clinical characteristics of the included normal controls and patients

From: The captopril challenge test for diagnosing primary Aldosteronism in a Chinese population

Ā 

NC (nā€‰=ā€‰40)

PH (nā€‰=ā€‰163)

IHA (nā€‰=ā€‰28)

APA (nā€‰=ā€‰82)

Age (y)

49.0ā€‰Ā±ā€‰11.5

48.6ā€‰Ā±ā€‰15.4

51.5ā€‰Ā±ā€‰10.9

46.0ā€‰Ā±ā€‰12.9

Sex (M/F)

19 / 21

92 /71

18 / 10

37 / 45

BMI (kg/m2)

25.0ā€‰Ā±ā€‰3.6

25.6ā€‰Ā±ā€‰4.0

25.2ā€‰Ā±ā€‰2.4

25.5ā€‰Ā±ā€‰8.9

SBP (mmHg)

124.2ā€‰Ā±ā€‰9.3

145.4ā€‰Ā±ā€‰19.6A

144.5ā€‰Ā±ā€‰13.4A

152.0ā€‰Ā±ā€‰20.8AB

DBP (mmHg)

75.1ā€‰Ā±ā€‰9.5

89.0ā€‰Ā±ā€‰14.4A

90.3ā€‰Ā±ā€‰11.9A

94.7ā€‰Ā±ā€‰15.3AB

Prevalence of hypokalemia (%)

ā€“

ā€“

75.0

92.7c

Serum potassium (mmol/L)

4.0ā€‰Ā±ā€‰0.29

4.0ā€‰Ā±ā€‰0.25

3.3ā€‰Ā±ā€‰0.45AB

3.2ā€‰Ā±ā€‰0.53AB

Serum sodium (mmol/L)

141.1ā€‰Ā±ā€‰1.9

141.0ā€‰Ā±ā€‰1.8

143.2ā€‰Ā±ā€‰2.3AB

143.5ā€‰Ā±ā€‰3.7AB

Urine potassium (mmol/24ā€‰h)

36.7ā€‰Ā±ā€‰12.9

38.9ā€‰Ā±ā€‰15.6

57.5ā€‰Ā±ā€‰27.0AB

58.2ā€‰Ā±ā€‰26.8AB

Supine PRA (ng/ml.h)

1.0 (0.55~1.9)

1.4 (0.65~2.4)

0.11 (0.03~0.26)AB

0.14 (0.025~0.33)AB

Supine PAC (ng/dl)

11.2ā€‰Ā±ā€‰4.7

12.7ā€‰Ā±ā€‰3.8

15.0ā€‰Ā±ā€‰6.1Ab

17.8ā€‰Ā±ā€‰5.5ABC

ARR

10.6 (5.4~17.1)

8.9 (5.4~17.5)

84.6 (64.6~556.2)AB

117.5 (49.4~695.8)AB

  1. Data are expressed as the meanā€‰Ā±ā€‰SD or median (25thā€“75th percentiles). NC normal controls, PH primary hypertension, IHA idiopathic hyperaldosteronism, APA aldosterone-producing adenoma, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, PRA plasma renin activity, PAC plasma aldosterone concentration, ARR aldosterone to renin ratio. APā€‰<ā€‰0.01, aPā€‰<ā€‰0.05 vs. NC; BPā€‰<ā€‰0.01, bPā€‰<ā€‰0.05 vs. PH; CPā€‰<ā€‰0.01, cPā€‰<ā€‰0.05 vs. IHA