Table 1 Difference analysis of basic clinical information between the nodule group and control group
From: Changes of serum 25(OH) D3 and IGF-1 levels in patients with thyroid nodules
Thyroid nodules | Control | P value | |
|---|---|---|---|
n | 289 | 109 | |
Age(year) | 46(40,53) | 45(40,49.5) | 0.351 |
Sex | 0.498 | ||
Male | 158(54.67) | 64(58.72) | |
Female | 131(45.33) | 45(41.28) | |
ALT(U/L) | 25.31 ± 19.57 | 26.38 ± 17.20 | 0.621 |
AST(U/L) | 21.03 ± 9.03 | 20.83 ± 7.10 | 0.841 |
r-GT(U/L) | 34.73 ± 36.59 | 32.46 ± 29.49 | 0.562 |
Uric(umol/L) | 314.39 ± 84.70 | 318.06 ± 78.24 | 0.694 |
FBG(mmol/L) | 5.42(5.07,5.94) | 5.20(4.92,5.43) | < 0.001 |
TC(mmol/L) | 5.17 ± 0.93 | 4.62 ± 0.86 | < 0.001 |
TG(mmol/L) | 1.25(0.84,1.99) | 1.13(0.81,1.69) | 0.195 |
HDL-C(mmol/L) | 1.29 ± 0.33 | 1.30 ± 0.29 | 0.764 |
LDL-C(mmol/L) | 2.58 ± 0.65 | 2.54 ± 0.66 | 0.628 |
BMI(kg/m2) | 25.63 ± 3.37 | 25.04 ± 3.70 | 0.129 |
WC(cm) | 88.19 ± 10.44 | 85.60 ± 11.41 | 0.032 |
Smoking | 0.239 | ||
Never | 197 (68.17) | 83(76.15) | |
Former | 16(5.54) | 3(2.75) | |
Current | 76(26.29) | 23(21.10) | |
Drinking | 0.021 | ||
Never | 151(52.25) | 48(44.034) | |
Former | 7(2.42) | 1(0.92) | |
Sometimes | 63(21.80) | 40(36.70) | |
Often | 68(23.53) | 20(18.34) | |
TT3(pmol/L) | 1.96 ± 0.35 | 2.09 ± 0.27 | < 0.001 |
TT4(pmol/L) | 111.62 ± 20.16 | 98.42 ± 15.19 | < 0.001 |
TSH(uIU/ml) | 1.89 ± 1.72 | 2.00 ± 0.98 | 0.366 |
TPOAb(IU/ml) | 10.54(6.82,15.89) | 11.74(8.23,16.85) | 0.139 |
FINS(uU/ml) | 9.93 ± 7.61 | 9.95 ± 5.26 | 0.971 |
25(OH)D3(ng/L) | 9.86 ± 6.66 | 12.74 ± 7.13 | < 0.001 |
IGF-1(ng/ml) | 111.10(81.53,165.44) | 192.65(96.38,313.49) | < 0.001 |
HOMA-IR | 1.96(1.25,3.19) | 2.20(1.52,2.82) | 0.929 |
Hypertention | 55(19.03) | 5(4.59) | < 0.001 |