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Table 1 Characteristics of subjects

From: HNF1A gene p.I27L is associated with early-onset, maturity-onset diabetes of the young-like diabetes in Turkey

 

Controls (n = 263)

Diabetics (n = 486)

P

Women (%)

58.2

51.5

0.081

Parent diabetes (%)

30.4

96.1

< 0.001

Symptoms at the diagnosis (%)

–

 

–

 Asymptomatic

 

58.1

 Diabetic symptom

 

32.5

 Gestational diabetes

 

8.1

 Diabetic complication

 

1.3

Treatment (%)

–

 

–

 Diet

 

20.1

 Oral antidiabetic

 

32.1

 İnsulin

 

47.8

Age at diagnosis (year)a

–

24.08 ± 4.82

–

BMI (kg/m2)a

27.01 ± 3.29

27.88 ± 5.72

0.109

Systolic BP (mmHg)a

124.70 ± 11.15

125.31 ± 11.82

0.823

Diastolic BP (mmHg)a

76.64 ± 7.21

75.61 ± 7.86

0.374

Fasting glucose (mg/dl)a

80.68 ± 9.37

151.75 ± 74.12

< 0.001

Postprandial glucose (mg/dl)a

–

252.92 ± 110.97

–

LDL (mg/dl)a

96.90 ± 20.75

107.99 ± 36.98

< 0.001

TG (mg/dl)a

99.51 ± 51.64

204.46 ± 203.21

< 0.001

Cholesterol (mg/dl)a

159.18 ± 27.68

193.55 ± 87.46

< 0.001

HDL (mg/dl)a

51.33 ± 16.96

44.16 ± 14.07

< 0.001

Creatinine (mg/dl)a

0.88 ± 0.89

1.24 ± 8.91

0.018

HbA1c (%)a

5.31 ± 0.10

8.21 ± 2.41

< 0.001

TSHa

1.74 ± 1.01

2.78 ± 8.73

0.142

HsCRPa

3.30 ± 2.98

4.08 ± 3.96

0.101

C-peptide (nmol/L)a

–

2.47 ± 1.79

–

Microalbuminuriaa

11.96 ± 13.65

94.86 ± 348.40

< 0.001

  1. BMI body mass index, HbA1c hemoglobin A1c, BP blood pressure
  2. aStudent’s t test was used for normally distributed continuous variables or log-transformed variables between two groups
  3. Data are shown as mean ± standard deviation (means ± SD) and percentage (%)
  4. Bold represents the significant p-values
  5. Categorical variables were analyzed with the Chi-square test or Fisher’s exact test, where appropriate