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Table 4 Parameter estimates of GEE model in women in 1st quartile of AMH compared to those of women in the 4th quartile

From: Overtime trend of thyroid hormones and thyroid autoimmunity and ovarian reserve: a longitudinal population study with a 12-year follow up

Variable

Parameter

β coef.

SE

95% confidence interval

P-Value

TSH (mu/L)

AMHQ1

−0.48

1.8

(−4.16,3.19)

0.79

AMHQ4

Reference

   

Time

0.33

0.44

(−0.53,1.21)

0.45

Time×AMHQ1

0.63

0.62

(−0.58,1.85)

0.30

Time×AMHQ4

Reference

   

FT4 (pmol/L)

AMHQ1

−1.15

0.38

(−2.05,-0.12)

0.02ª

AMHQ4

Reference

   

Time

0.38

−0.11

(−0.64,-0.12)

< 0.001ª

Time×AMHQ1

Time×AMHQ4

0.29

0.16

(−0.10,6.34)

0.06

Reference

   

TPO Ab+

AMHQ1

2.05

0.62

(1.31, 3.74)

0.01ª

AMHQ4

Reference

   

Time

1.10

0.05

(1.004,1.22)

0.04ª

 

Time×AMHQ1

0.93

0.06

(0.81,1.06)

0.28

Time×AMHQ4

Reference

   
  1. AMHQ1 AMH (Anti- mullerian hormone) in women of 1st quartile, AMHQ4 AMH in women of 4th quartile, BMI body mass index, FT4 free thyroxin level, TSH thyroid stimulating hormone, TPO Ab Thyroid peroxidase antibody, TPO Ab+ Thyroid peroxides antibody positivity, × indicates interaction