Table 4 Intraoperative and postoperative findings
From: Calcitonin negative Medullary Thyroid Carcinoma: a challenging diagnosis or a medical dilemma?
Author | Surgery | Tumor grading | Follow-up | Recurrence | CT-IHC | CGRP-IHC | CgA-IHC | Syn-IHC | TG-IHC | CEA-IHC | RET mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|
Sobol | TT | WDMTC | 6 month | Lymph nodes, liver and bone | – | – | + | NA | NA | + | NA |
Schmid 1 | NA | WDMTC | NA | NA | NA | + | + | NA | – | – | NA |
Schmid 2 | NA | WDMTC | 19 month | Lymph nodes | NA | + | + | NA | – | – | NA |
Schmid 3 | NA | WDMTC | NA | NA | NA | – | + | NA | – | – | NA |
Schmid 4 | NA | WDMTC | NA | NA | NA | – | + | NA | NA | – | NA |
Redding | TT + LYA | WDMTC | 43 month | Negative | + | NA | NA | + | NA | + | – |
Bockhorn | TT + LYA | PDMTC | NA | NA | NA | NA | + | NA | – | + | + |
Sand | TT + LYA | PDMTC | Deceased 6 weeks | NA | NA | NA | NA | NA | NA | NA | NA |
Dora | TT | PDMTC | NA | NA | + | NA | + | + | – | NA | – |
Wang | NA | WDMTC | 12 months | Negative | + | NA | + | NA | – | + | NA |
Giovanella | TT + LYA | WDMTC | 24 months | NA | + | NA | NA | NA | NA | NA | NA |
Alapat | TT + LYA | WDMTC | 20 months | Negative | + | NA | + | NA | – | + | NA |
Chernyavsky | TT + LYA | WDMTC | 12 months | Negative | – | NA | + | + | + | NA | + |
Nakazawa | TT | WDMTC | 18 months | Negative | NA | NA | + | + | – | NA | NA |
Frank-Raue 1 | ET | WDMTC | 72 months | Negative | + | NA | + | + | – | + | – |
Frank-Raue 2 | NA | WDMTC | 25 months | Pulmonary | + | NA | + | + | – | + | – |
Frank-Raue 3 | NA | WDMTC | 150 months | Lymph modes | + | NA | + | + | – | + | + |
Frank-Raue 4 | NA | PDMTC | 18 months | Local tumor infiltration | + | NA | + | + | – | + | – |
Frank-Raue 5 | NA | WDMTC | 21 months | Lymph node, bone, brain | + | NA | + | + | – | + | + |
Frank-Raue 6 | NA | PDMTC | 21 months | Pulmonary | + | NA | + | + | – | + | + |
Frank-Raue 7 | NA | PDMTC | 36 months | Dead because of pulmonary failure | + | NA | + | + | – | + | + |
Ismi | NA | PDMTC | NA | NA | – | NA | + | + | – | NA | NA |
Brutsaert | TT + LYA | WDMTC | NA | NA | NA | NA | NA | NA | NA | NA | + |
Kim | ET | PDMTC | 12 months | Negative | – | NA | + | + | + | – | – |
Kasajima | NA | WDMTC | NA | NA | NA | + | + | + | NA | NA | – |
Samà 1 | TT | NA | 120 months | Negative | + | NA | + | NA | NA | + | – |
Samà 2 | NA | NA | 120 months | Negative | NA | NA | NA | NA | NA | NA | NA |
Samà 3 | NA | NA | 36 months | Negative | – | NA | – | NA | NA | – | + |
Samà 4 | NA | NA | 36 months | Negative | + | NA | + | NA | NA | – | – |
Parmer | TT | WDMTC | NA | NA | – | NA | + | + | – | + | NA |
Zhou | NA | NA | NA | NA | + 8 cases - 11 cases | NA | + 18 cases - 1 case | + 19 cases | + 5 cases - 14 cases | + 4 cases - 15 cases | NA in 15 cases - In 4 cases |