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Table 4 Comparison of delta cortisol in diabetes subjects and control

From: 11β Hydroxysteroid dehydrogenase – 1 activity in type 2 diabetes mellitus: a comparative study

factor Delta cortisol Cases (mcg/dl) Delta cortisol control
(mcg/dl)
P value
Age (n)
 < 35 (20) 13 5.4 0.005
 35–50 (31) 12 9 0.08
 > 50 (08)    -
BMI (n)
 < 23 (19) 14.2 8.9 0.017
 23–27 (29) 11.3 9.1 0.142
 > 27 (12) 9 8.2 0.755
Physical activity(n)
 Sedendary (15) 16 11 0.06
 Intermediate(18) 13.4 10.2 0.083
 Exercise (27) 15.1 6.2 0.004
Calorie intake
 < 1600 (8) 11.2 6.1 0.052
 1600–1900 (18) 12.3 8.2 0.08
 1900–2200 (21) 12 8.2 0.03
 2200–2500 (7) 9 8.4 0.3
 > 2500 (6) 8 8.3 0.24
  1. Mann-Whitney test was used to compare delta cortisol between cases and control as shown above
  2. Delta cortisol was increased in diabetics as compared to healthy controls and was statistically significant in those subjects < 35 years of age (p = 0.005), BMI < 23 (p = 0.017) and in those who exercise (p = 0.004)
  3. When delta cortisol was compared in various calorie groups, it was significantly more in diabetics. However, when Kruskal Wallis test applied, the difference was not significant. Also see Fig. 3
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