11β Hydroxysteroid dehydrogenase – 1 activity in type 2 diabetes mellitus: a comparative study

BMC Endocrine Disorders

Table 2 Fasting lipid profile, liver & renal function tests of the study subjects

Lipid profile by automated analyser or ELISA method. All other tests by ELISA	cases and control				p-value
	diabetes		healthy controls
	Mean	Standard Deviation	Mean	Standard Deviation
total cholesterol (mg/dl)	171	35	185	42	0.84
LDL (mg/dl)	107	30	120	27	0.08
HDL (mg/dl)	41	10	41	10	NS
Total triglyceride (mg/dl)	151	50	143	49	0.65
Total bilirubin (mg/dl)	1.0	.4	.9	.1	0.4
SGOT (U/L)	41	16	34	20	0.029
SGPT (U/L)	36	14	31	11	0.20
S. Albumin (U/L)	4.5	.7	4.7	.4	0.069
S.Globulin (U/L)	3.3	.6	3.0	.0	0.07
Alkaline phosphatase	163	62	103	67	,0.01
S.creatinine (mg/dl)	.9	.1	.9	.1	NS
25 (OH) vitamin D	18.4	7.4	23	12.3	0.021

t-test was done for parametric variables (Total Cholesterol, LDL,HDL,Triglycerides, alkaline phosphatase)
Mann-Whitney test was done for non-parametric variables (Bilirubin, SGOT<SGPT,Albumin, Globulin,creatinine, 25(OH)vitamin D)
Diabetic subjects have higher mean Alkaline phosphatase (ALP),Serum Glutamate oxaloacetate transferase (SGOT), Serum Glutamate Pyruvate Transferase (SGPT) and lower 25(OH) vitamin D, but better mean lipid parameters as compared to controls

ISSN: 1472-6823