Performance of HbA1c versus oral glucose tolerance test (OGTT) as a screening tool to diagnose dysglycemic status in high-risk Thai patients

Table 1 Clinical characteristics and laboratory data of analyzed subjects classified by OGTT (N = 512)

	Overall (n = 512)	NGT (n = 220, 42.9%)	IGT (n = 191, 37.3%)	DM (n = 101, 19.7%)	p-value
Female (%)	60.5%	58.6%	58.6%	68.3%	0.205
Age (years)	50.3 ± 12.7	48.4 ± 12.8	50.3 ± 11.4	54.3 ± 14	0.001
BMI (kg/m²)	26.5 ± 4.6	26.1 ± 4.7	26.7 ± 4.5	27.0 ± 4.6	0.189
Systolic BP (mmHg)	126 ± 16	124 ± 16	126 ± 15	131 ± 15	< 0.001
Diastolic BP(mmHg)	74 ± 11	74 ± 11	75 ± 11	74 ± 11	0.578
Fasting plasma glucose	103 ± 12	98 ± 9	103 ± 11	112 ± 15	< 0.001
2-h plasma glucose	155 ± 51	111 ± 19	163 ± 17	236 ± 29	< 0.001
Hypertension	31.8%	27.7%	32.5%	39.6%	0.103
History of smoking	10.4%	11.0%	11.1%	7.9%	0.422
Statin usage	37%	34%	40%	40%	0.370
History of CVD	2.3%	1.8%	2.1%	4.0%	0.339
Family History of DM	60.2%	57.7%	59.7%	66.3%	0.339
HbA1c (%NGSP)	5.8 ± 0.5	5.6 ± 0.4	5.8 ± 0.5	6.1 ± 0.5	< 0.001
Total Cholesterol (mg/dL)	199 ± 39	199 ± 39	198 ± 40	200 ± 36	0.949
Fasting Triglyceride (mg/dL)	138 ± 83	128 ± 75	149 ± 102	138 ± 48	0.081
HDL (mg/dL)	53 ± 15	55 ± 16	51 ± 15	52 ± 12	0.048
LDL (mg/dL)	125 ± 37	125 ± 38	126 ± 39	124 ± 30	0.883
VFA^a (cm²)	130 ± 39	129 ± 41	131 ± 39	129 ± 34	0.963
WC (cm)	94.5 ± 13	94.1 ± 13	94.9 ± 13	94.7 ± 12	0.909
Thai DM risk score (points)	9 ± 4	8 ± 4	9 ± 3	10 ± 3	0.003
Thai CV risk score^b (points)	4 (1–10)	3 (1–7)	4 (1–9)	10 (2–19)	< 0.001

^a Available in 268/512 overall subjects (107/220 in NGT, 112/191 in IGT, 49/101 in DM)
^b Displayed as median (IQR)

ISSN: 1472-6823