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Table 1 Characteristics of the MDC CV Re-exam Cohort and Participants classified as NGT, Pre-diabetes and Diabetes

From: Pre-diabetes and diabetes are independently associated with adverse cognitive test results: a cross-sectional, population-based study

 

Total study sample (n = 2994)

NGT (n = 1539)

Pre-diabetes (n = 902)

Diabetes (n = 553)

P-value (df = 3)

Covariates

 Age (years)

72.4 (5.58)

71.8 (5.56)

73.0 (5.70)

72.9 (5.31)

< 0.001

 Sex (men/women, %)

40.2/59.8

35.7/64.3

43.3/56.7

47.9/52.1

< 0.001

Educational level (%)

 Low (≤ 10 years)

68.6

66.5

71.4

70.2

0.089

 Medium (11–12 years)

9.46

9.62

9.20

9.40

 High (> 12 years)

22.2

23.8

19.4

20.4

Physical activity (%)

 Sedentary spare time

7.08

5.20

7.76

11.2

< 0.001

 Moderate exercise

75.7

74.3

77.9

76.0

 Regular exercise

17.2

20.5

14.3

12.7

Smoking status (%)

 Never-smokers

45.3

46.8

44.4

42.8

0.105

 Past smokers

45.0

44.6

43.9

48.0

 Present smokers

9.65

8.64

11.6

9.19

Alcohol consumption (%)

 No consumption

23.1

20.3

24.6

28.2

< 0.001

 Moderate consumption

64.4

67.8

62.1

58.6

 High consumption

12.5

11.9

13.3

13.2

Systolic BP (mmHg)

143.2 (18.9)

141.4 (18.9)

143.8 (18.9)

147.4 (18.3)

< 0.001

Waist circumference (cm)

92.2 (12.5)

89.2 (11.5)

93.5 (12.4)

98.4 (11.5)

< 0.001

Heart rate (beats/min)

67.4 (11.1)

66.5 (10.4)

68.0 (11.4)

69.2 (12.0)

< 0.001

Pulse wave velocity (m/s)

10.5 (2.66)

10.2 (2.72)

10.7 (2.92)

11.3 (3.15)

< 0.001

Total cholesterol (mmol/l)

5.21 (1.07)

5.49 (1.01)

5.06 (1.03)

4.64 (1.05)

< 0.001

Fasting glucose (mmol/l)

6.09 (1.28)

5.46 (0.443)

6.17 (0.523)

7.77 (2.01)

< 0.001

2-h glucose (mmol/l)a

7.11 (1.54)

5.82 (1.16)

8.01 (1.65)

11.7 (0.02)

< 0.001

MMSE full test (/30p)

28.3 (1.81)

28.3 (1.65)

28.0 (1.83)

27.9 (2.00)

<.0001

AQT full test (time, s)

135.8 (32.3)

132.1 (28.3)

138.3 (33.7)

142.0 (38.6)

< 0.001

MMSEmemory score (/13p)

12.1 (1.02)

12.2 (0.957)

12.0 (1.05)

12.0 (1.11)

< 0.001

AQTspeed (Part 1–2) (time, s)

62.8 (14.5)

61.1 (12.9)

64.0 (14.8)

65.7 (17.2)

< 0.001

AQTexecutive (Part 3)(time, s)

73.0 (19.7)

71.0 (17.3)

74.4 (20.7)

76.3 (23.4)

< 0.001

  1. Significant p-values are highlighted in bold text
  2. a For 2-h glucose (for which missing data was not imputed) n = 2671 for the total cohort, n = 1523 for NGT, n = 895 for pre-diabetes and n = 253 for diabetes