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Table 2 Patient characteristics stratified by MCI

From: Low vitamin D levels are associated with cognitive impairment in patients with Hashimoto thyroiditis

Characteristics

Patients with MCI

Patients without MCI

P

Number of patients

55

139

Age (years), mean ± (SD)

46.7 ± 9.0

50.5 ± 9.9

0.014

Sex (female/male)

13/42

23/116

0.252

Educaton (years), median (IQR)

13 (8–17)

11 (8–14)

0.074

BMI (kg/m2), mean ± (SD)

23.6 ± 3.1

24.5 ± 3.2

0.092

TSH (IU/mL), mean ± (SD)

2.3 ± 0.8

2.1 ± 0.9

0.336

FT3 (pmol/L), mean ± (SD)

4.7 ± 1.0

4.8 ± 1.1

0.541

FT4 (pmol/L), mean ± (SD)

17.9 ± 3.9

18.2 ± 4.6

0.710

TPOAbs (IU/mL), median (IQR)

210.1 (105.0–280.8)

175.4 (100.6–280.6)

0.244

TgAbs (IU/mL), median (IQR)

221.2 (201.5–282.3)

213.5 (190.3–248.5)

0.135

25(OH)D (nmol/L), mean ± (SD)

33.9 ± 6.2

44.3 ± 9.6

< 0.001

25(OH)D, No. (%)

  

< 0.001

 Quartile 1 (30.8 nmol/L)a

29 (52.7)

20 (14.4)

< 0.001

 Quartile 2 (36.6 nmol/L)a

14 (25.5)

31 (23.3)

0.639

 Quartile 3 (43.7 nmol/L)a

10 (18.2)

40 (28.8)

0.128

 Quartile 4 (53.1 nmol/L)a

2 (3.6)

48 (34.5)

< 0.001

  1. Data are expressed as number (percentage) or means (± SD) or medians (IQR). Abbreviations: MCI Mild cognitive impairment, BMI Body mass index, TSH Thyroid-stimulating hormone, FT3 Free-triiodothyronine, FT4 Free thyroxine, TPOAbs Anti-thyroid peroxidase antibodies, TgAbs Antithyroglobuline antibodies, 25(OH)D 25-hydroxyvitamin D
  2. aThe median 25-hydroxyvitamin D values for each quartile