Fig. 1

Endocrine imaging of a patient with Burkitt’s lymphoma. Thyroid US showed a solid hypoechoic mass (a) with significant internal vascularity (b) and no calcifications. Core needle biopsy showed homogeneous medium-sized B cells infiltrating the thyroid (c, arrowhead), mitotic figures (c, asterisk), and scattered macrophages ingesting apoptotic cells (c, arrow), giving a “starry sky” appearance. The extent of thyroid infiltration can be appreciated on (d) where follicular cells are only those positively stained for TTF1 (thyroid transcription factor 1). The CT scan performed before treatment showed a 44x43x87 mm thyroid nodule (e), which disappeared at the CT scan performed one year after treatment completion (f)