Fig. 2

Growth Velocity of Patient with Attenuated MPS I from Case Study Relative to Growth Standards. Growth velocity by age is shown by the blue markers with timing and duration of leuprolide acetate (L), growth hormone (GH) and laronidase (LAR) treatments indicated. Treatment doses are the same as shown in Fig. 1. Percentiles for boys maturing at average time or for late maturers are shown as adapted from Tanner JM and Davies PS. Clinical longitudinal standards for height and height velocity for North American children [50]