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Table 3 Multivariate regression of cardiovascular risk factors and C-Peptide at 23 and 30 years olda

From: C-Peptide and cardiovascular risk factors among young adults in a southern Brazilian cohort

Cardiovascular risk factors

1st quartile

2nd quartile

3rd quartile

4th quartile

μ (CI95%)

β (CI95%)

β (CI95%)

β (CI95%)

 

23 years

Anthropometric

 Waist circumference (cm)

Reference

0.88 (− 0.46; 2.22)

1.78 (0.41; 3.15)

4.90 (3.45; 6.36)

Reference

0.49 (−0.38; 1.02)

0.97 (0.44; 1.52)

2.15 (1.57; 2.72)

Metabolic

 Serum glycaemia (mg/dL)

Reference

2.58 (0.67; 4.50)

5.55 (3.60; 7.49)

11.19 (9.80; 13.94)

 Total cholesterol (mg/dL)

Reference

−0.38 (−5.04; 4.28)

0.95 (−3.79; 5.70)

1.76 (− 3.28; 6.80)

 HDL cholesterol (mg/dL)

Reference

−2.12 (−3.80; − 0.44)

− 2.33 (− 4.04; − 0.61)

− 2.10 (− 3.93; − 0.29)

 Triglycerides (mg/dL)

Reference

1.12 (1.05; 1.20)

1.19 (1.05; 1.20)

1.28 (1.19; 1.38)

 C-reactive protein (mg/dL)

Reference

0.94 (0.81; 1.10)

1.26 (1.08; 1.47)

1.42 (1.20; 1.67)

Hemodynamic

 Systolic pressure (mmHg)

Reference

−1.32 (−3.39; 0.75)

− 1.93 (−4.05; 0.18)

−0.25 (−2.48; 2.01)

 Diastolic pressure (mmHg)

Reference

−1.88 (− 3.43; − 0.32)

−1.93 (− 3.52; − 0.35)

−0.20 (− 1.88; 1.47)

 

30 years

Anthropometric

 Waist circumference (cm)

Reference

1.0 (−0.39; 2.41)

1,74 (0.30; 3.17)

4.18 (2.65; 5.70)

 Body mass index

Reference

0.75 (0.15; 1.34)

1.26 (0.65; 1.88)

2.26 (1.61; 2.91)

Metabolic

 Serum glycaemia (mg/dL)

Reference

−1.28 (−3.18; 0.62)

−0.39 (−2.33; 1.55)

−0.66 (− 2.72; 1.40)

 Glycated hemoglobin (%)

Reference

0.06 (0.01; 0.12)

0.07 (0.02; 0.13)

0.07 (0.01; 0.14)

 Total cholesterol (mg/dL)

Reference

−0.62 (−4.93; 3.68)

−0.69 (−5.11; 3.71)

−2.20 (−6.88; 2.47)

 HDL cholesterol (mg/dL)

Reference

−0.79 (−2.42; 0.84)

−1.30 (− 2.97; 0.36)

−1.82 (− 3.59; − 0.05)

 LDL cholesterol (mg/dL)

Reference

−0.76 (− 4.23; 2.70)

−0.68 (− 4.23; 2.86)

−0.98 (− 4.75; 2.78)

 Triglycerides (mg/dL)

Reference

1,06 (0,99; 1,13)

1,07 (1,0; 1,14)

1,06 (0,99; 1,14)

 C-reactive protein (mg/dL)

Reference

1,23 (1,06; 1,42)

1,51 (1,30; 1,75)

1,54 (1,32; 1,80)

Hemodynamic

 Systolic pressure (mmHg)

Reference

−0.96 (−2.54; 1.62)

−0.25 (−1.87; 1.36)

−0.03 (− 1.75; 1.68)

 Diastolic pressure (mmHg)

Reference

−0.44 (−1.53; 0.65)

0.45 (− 0.66; 1.56)

1.12 (− 0.06; 2.30)

  1. μ geometric mean
  2. aadjusted for: time of fasting, physical activity practice per week (minutes), family income, mother’s skin color, birthweight, rapid growth between 2 and 4 years old, smoking at 23 years, alcohol consumption, family history of dyslipidemia, arterial hypertension and stroke, myocardial infarction
  3. Values presented in bold present statistical significance