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Table 1 Patient clinico-biochemical features

From: Estrogen receptor 1 gene polymorphisms are associated with metabolic syndrome in postmenopausal women in China

Variables

Metabolic syndrome (n = 150)

No metabolic syndrome (n = 154)

P

Age (years)

63.0 ± 4.1

62.9 ± 4.8

0.751

BMI (kg/m2)

25.4 ± 2.9

22.5 ± 3.0

<0.001

Waist circumference (cm)

88.3 ± 5.2

81.9 ± 2.5

0.001

FBG (mM)

7.1 ± 1.4

5.2 ± 0.7

<0.001

HbA1C (%)

6.7 ± 0.9

5.2 ± 0.4

0.003

Systolic blood pressure (mmHg)

148.1 ± 6.9

122.1 ± 4.9

<0.001

Diastolic blood pressure (mmHg)

92.3 ± 4.5

71.8 ± 5.7

0.002

Triglycerides (mM)

2.4 ± 1.1

1.8 ± 1.2

<0.001

Total cholesterol (mM)

5.1 ± 1.0

4.6 ± 1.1

<0.001

HDL-C (mM)

1.0 ± 0.1

1.3 ± 0.1

<0.001

LDL-C (mM)

3.1 ± 0.9

2.8 ± 0.6

0.008

NAFLD (%)

110(73.3)

33 (21.4)

<0.001

Fasting serum insulin (μIU/mL)

14.3 ± 7.2

9.2 ± 5.0

<0.001

Estradiol (pg/ml)

23.2 ± 7.2

27.0 ± 7.2

<0.001

HOMA-IR

3.5 ± 1.8

2.1 ± 1.3

<0.001

  1. Abbreviations BMI body mass index, FBG fasting blood glucose, HbA1C hemoglobin A1C, HDL high density lipoprotein, LDL low-density lipoprotein, NAFLD nonalcoholic fatty liver disease
  2. Data are mean ± SD. Comparisons were performed by t-test
  3. p < 0.05 indicates a significant difference from the normal control